Clinical Observation Of Qianjinweijing Decoction And Sangbaipi Decoction On Acute Exacerbation Of Chronic Obstructive Pulmonary Disease (Phlegm Heat In The Lung Syndrome) And Its Influence On Procalcitonin

Objective:This study was to observe the clinical therapeutic effect of Qianjin Weijing Decoction and Sangbaipi Decoction in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)(phlegmheat obstructing the lung syndrome).The safety and efficacy of Sangbaipi Decoction were objectively evaluated,highlighting its clinical treatment advantages,and providing objective basis for the wider clinical application of Qianjinweijing Decoction and Sangbaipi Decoction in the treatment of AECOPD.Methods:The case screening of this study was based on a total of 67 patients who were treated in Minzhu Hospital of Daowai District,Harbin City,Heilongjiang Province from January to December 2020.They were divided into 34 cases in the control group and 33 cases in the treatment group according to the random number table method.One patient in the treatment group dropped out during the study,and 2 patients in the control group dropped out during the study.A total of 64 patients successfully completed the clinical trial.Both groups of patients were treated with conventional western medicine therapy,while the treatment group was treated with Qianjinweijing Decoction and Sangbaipi Decoction at the same time,and the course of study was 10 days.SPSS21.0 was used to compare the TCM symptom scores,pulmonary function(FEV1/FVC,FEV1%pred),procalcito-nin indexes,and safety indexes(WBC,ECG,AST,ALT,Cr,BUN,RBS,ESR)of the two groups of patients before and after treatment were compared and analyzed,and the clinical efficacy of Qianjinweijing Decoction and Sangbaipi Decoction was objectively evaluated.Results:1.After treatment,the total scores of clinical symptoms and signs in the treatment group and control group were improved compared with those before treatment,and the difference was statistically significant(P<0.05).The comparison between the two groups showed that the curative effect of the treatment group was significantly better than that of the control group,and the difference was statistically significant(P<0.01).There were statistically significant differences in cough,wheezing,cyanosis of lips,expectoration,fever,thirst for cold drinks,and lung rales between the two groups(P<0.05).The difference did not show statistical significance(P>0.05),while the treatment group had statistical difference(P<0.05).After treatment,the comparison between the two groups showed that the treatment group was better than the control group in terms of individual symptoms and signs,and the difference was statistically significant(P<0.05);2.After treatment,the total scores of symptoms and signs in the two groups showed a downward trend,and the curative effect of the treatment group was better than that of the control group,with statistical significance(P<0.05);3.The total effective rate of the treatment group(90.6%)was higher than that of the control group(71.9%),and the difference was statistically significant(P<0.05);4.The intra-group comparison of pulmonary function between the two groups before and after treatment showed a statistical difference(P<0.05).After treatment,the comparison between the treatment group and the control group showed that the differences in FEV1%and FEV1/FVC(%)were statistically significant(P<0.05);5.Comparing the PCT results between the two groups before treatment,the treatment group was significantly better than the control group,and the difference was statistically significant(P<0.05).),and further compared the changes of PCT in the two groups before and after treatment,both groups showed statistical significance(P<0.05),both groups were significantly decreased,and the treatment group decreased more significantly than the control group.Conclusion:Qianjinweijing decoction combined with Sangbaipi decoction combined with western medicine can effectively improve the clinical symptoms and signs of patients with acute exacerbation of chronic obstructive pulmonary disease(phlegm-heat obstructing the lung syndrome),and the curative effect is significantly better than that of the control group.The effect of dry stool symptoms is particularly prominent,improving lung function,reducing PCT,promoting inflammatory absorption,increasing oxygen partial pressure and reducing carbon dioxide partial pressure,and significantly improving the patient’s apparent efficiency and total effective efficiency.