Objective: To study the RCT of fengre pneumonia granule + Hu atan powder combined with conventional western medicine in the t reatment of children with community-acquired pneumonia(wind heat closed lung syndrome),and to verify the effectiveness and safety of integrated traditional Chinese and Western medicine in thetre atment of children with community acquired pneumonia-bronchopneu monia(syndrome of wind-heat invading lung).Methods:children who were hospitalized in the Affiliated Hos pital of Shandong University of traditional Chinese medicine,Sha ndong Provincial Hospital,Qilu Hospital of Shandong University,Q ilu children’s Hospital of Shandong University,Jinan maternal an d child health hospital and the pediatric ward of Jining first p eople’s Hospital from December 2020 to December 2021 and met the diagnostic criteria of Western medicine for bronchiolitis and tr aditional Chinese medicine for asthma and cough of pneumonia(win d heat closed lung syndrome),A total of 191 cases.The selectedca ses met the inclusion criteria and were randomly divided into th e observation group(Western medicine treatment scheme+oral admin istration of fengre pneumonia granule+external application of Hu atan powder)and the control group(Western medicine treatmentsche me+oral administration of traditional Chinese medicine simulant+external application simulant)with 98 cases.The daily fever,cou gh,nasal congestion,asthma,lung auscultation and other condition s of the enrolled children were observed and recorded,and the le ngth of hospital stay,hospitalization expenses,examination resul ts and other conditions of the children were recorded.By observi ng the changes of syndrome scores and relevant records of childr en in the two groups,the curative effects of the two groups were evaluated through statistical analysis.Results:1.Clinical efficacy analysis:(1)the overall disease efficacy of the observation group was higher than that of the co ntrol group(P < 0.05);(2)There was no significant difference in the curative effect of TCM syndromes between the observation gro up and the control group(P > 0.05);(3)Clinical end point time:th e clinical end point time of the observation group was lower tha n that of the control group(P<0.05);(4)The observation group and the control group could reduce the disease score after 3 days of treatment,but there was no significant difference in the degree of reduction;After 5 days of treatment,the observation group w as better than the control group(P<0.05);(5)After 3 days of trea tment,both the observation group and the control group couldredu ce the disease score,but there was no significant difference in the degree of reduction(P>0.05);After 5 days of treatment,the observation group was better than the control group(P<0.05).2.A nalysis of main symptoms and signs:after treatment,the observati on group and the control group improved in fever,cough,expecto ration,asthma and pulmonary auscultation(P<0.05).There was no significant difference between the two groups in the improvement of fever,cough and pulmonary auscultation(P>0.05),but the obser vation group was significantly better than the control group in the improvement of expectoration and asthma(P <0.05).3.Analysis of secondary symptoms and signs:after treatment,the observation group had a good improvement in runny nose,sweating,complexion,n ausea and vomiting,pharynx,spirit,sleep,diet and dry stool(P<0.05);The control group had excellent improvement in runny nose,sweating,complexion,pharynx,spirit,sleep,diet and dry stool(P<0.05).The observation group was better than the control group in i mproving complexion and diet(P<0.05).4.Analysis of hospitalizati on expenses:the hospitalization expenses of the observation grou p were lower than those of the control group(P<0.05);5.Safety an alysis:the observation group and the control group had obvious a dverse reaction events.There were no obvious abnormalities in li ver and kidney function and ECG before and after treatment.Conclusion: 1.The onset of cap in children has no significan t correlation with gender and the onset age is concentrated in 3-5 years old.2.Fengre pneumonia granule+Huatan powder combined w ith western medicine in the treatment of cap(wind heat closingl ung syndrome)has definite clinical efficacy.Itis a reliable,sa fe and effective scheme for the treatment of this disease.3.Thec linical application of fengre pneumonia granule+Huatan powdercom bined with western medicine in the treatment of cap(wind heat c losing the lung syndrome)has significantlyimproved the clinical symptoms of children,improved the clinical curative effect,shor tened the course of treatment,reduced the hospitalization expen ses and reduced the family burden.4.There are almost no adverse reactions in the clinical application of fengre pneumonia granul e+Huatan powder combined with western medicine in the treatment of cap(wind heat closing lung syndrome),which is well accepted and safe by children and their families. |