Observation On The Clinical Effect Of Smokeless Moxibustion On Cancer-related Fatigue With Deficiency Of Both Qi And Blood

ObjectiveTo observe the clinical effect of smokeless moxibustion on cancer-related fatigue(CRF)of Qi and blood deficiency type,and to provide a new idea for its clinical treatment.MethodsDivide 60 patients who is CRF(60)into two groups,named the one is treatment group(30)the other is control group(30)by means of random control.Giving the control group western medicine,and on the meantime adding smokeless moxibustion(both sides Zusanli,Guanyuan and Qihai)on the methods of control group to the treatment group,and both two treatment lasted for 4 weeks.Using the TCM symptom score table,Piper fatigue scale,EORTC-QLQ-C30 and blood test result to evaluate its function,safety and the quality of life.Results1.Baseline comparison:Baseline comparison was made between the two groups,including age,gender,tumor type composition,tumor stage,treatment,TCM symptom point table,Piper fatigue scale,EORTC-QLQ-C30 and corresponding peripheral blood test result.From the results of statistics it’ easy to find that there was no significant difference between the two groups(P>0.05).2.Symptoms of TCM:Comparison groups: palpitation,numbness of hands and feet,pale complexion,sleepness in the control group were different than before(P<0.05,P<0.01).The improvement of symptoms was also different in the treatment group(P<0.05,P<0.01).Except palpitation and less menstrual,the rest of symptons was better than the control group.The point of TCM symptoms in two groups were improved(P<0.05,P <0.01).Comparison between groups: the mayjor symptom in the treatment group was better than that in the control group;the total scores of TCM symptoms were improved significantly(P<0.05).3.Piper Fatigue Scale:In-group comparisons: the affective and cognitive fatigue dimension in the control group was statistically significant than before(P<0.05,P<0.01).In the other group,behavioral,emotional,physical and cognitive fatigue were better(P<0.01).The total score of fatigue was significantly different than before(P<0.01).Comparison between groups: the differences in behavioral,emotional,physical and cognitive fatigue in the treatment group were statistically significant(P<0.05).the total fatigue score had statistical significance in the treatment group(P<0.01).4.The EORTC-QLQ C30 :Control group: except social function,shortness of breath and constipation,other functions and symptoms in the control group was significantly different from that before treatment(P<0.05,P<0.01).In the treatment group,the improvement of other functions was significantly different from that before treatment(P<0.05,P<0.01).Comparison between groups: the treatment group is better than than the other group in the function and symptoms control group.(P<0.05).5.Blood test result:In-group comparison: there was no significant difference in the serum data of the control group before treatment(P>0.05).The WBC,neut and ALB of the treatment group were significantly different from those before treatment(P<0.05),and the WBC(5.00±2.52 VS 5.98±3.98)、NEUT(3.06±2.24 VS 4.06±0.74)showed an upward trend;In addition,HGB(110.98±26.21 VS 113.83±19.12)although the improvement was not statistically significant(P>0.05),it also showed an upward trend.Conclusion1.Smokeless moxibustion can improve the deficiency of qi and blood symptoms of CRF,reduce the fatigue level,and improve the quality of standard living.2.Moxibustion of Zusanli,Guanyuan and Qihai acupoints can hosit patients’ nausea and vomiting symptoms,WBC level,weaken the toxic and side effects which were brought by radiotherapy and chemotherapy,and moxibustion can be used as an auxiliary method for the anti-tumor treatment.