Objective:1.Systematically summarize Professor Cai Lin’s academic thoughts on spleen and stomach diseases,so as to better carry out the inheritance and innovation of traditional Chinese medicine.2.Through collecting cases in outpatient department and using data mining,we summarized the medication rules of Professor Cai Lin in the diagnosis and treatment of chronic gastritis,and provided new ideas for clinical diagnosis and treatment of chronic gastritis.Method:1.By studying Huangdi Neijing,treatise on febrile diseases,treatise on spleen and stomach and other ancient books,combing the ancient academic thoughts of spleen and stomach diseases,combined with outpatient prescription copying,reading tutor’s thesis,tutor’s interview and other forms,carefully experience tutor’s ideas of disease differentiation and treatment,prescription and medication,systematically summarize tutor’s academic thoughts of spleen and stomach diseases.2.Input the prescription information of 172 patients with chronic gastritis into excel,establish the database,and use SPSS 23.0 and SPSS modeler 18.0 software to mine the medication rules of chronic gastritis.Result:1.Professor Cai Lin’s academic thought of spleen and stomach disease originated from the discussion of physiology and pathology of spleen and stomach in classic works such as Huangdi’s Internal Classic,treatise on febrile diseases,treatise on spleen and stomach,and clinical guide medical records.In particular,Professor Cai Lin was deeply influenced by the academic thought of "internal injury to the spleen and stomach,all kinds of diseases are born".Combined with long-term clinical practice,Professor Cai Lin has formed his own academic view on the treatment of spleen and stomach diseases,especially focusing on Spleen Yang.2.General situation:172 cases of chronic gastritis were collected in this study,62 cases were male,110 cases were female,the ratio of male and female was 1:1.77.The age of patients ranged from 14 to 83 years old,among which 61 patients aged from 51 to 60 years old accounted for 35.47%.3.Frequency analysis:a total of 118 kinds of traditional Chinese medicine were used in 172 prescriptions,with a total frequency of 2863 times.The top ten herbs were Poria cocos,Atractylodes macrocephala,Codonopsis pilosula,Zhigancao,bupleurum,perilla leaf,rice bud,Pinellia ternata,Magnolia officinalis and Evodia rutaecarpa.The first 22 high-frequency traditional Chinese medicines were sorted in terms of their nature,taste,and efficacy.The four Qi were warm,calm,cold,and hot;the five flavors were pungent,bitter,sweet,salty,and sour;the meridian was spleen,stomach,lung,liver,heart,kidney,large intestine,gallbladder,Sanjiao,and bladder;the efficacy was tonifying deficiency,relieving exterior,resolving phlegm,promoting water and dampness,warming interior,resolving dampness,regulating qi,and Xiaoshi Medicine,hemostatic medicine,antipyretic medicine,Qufengshi medicine.4.Cluster analysis:cluster analysis was used to cluster high-frequency traditional Chinese medicine,and five cluster combinations were obtained.The first category:Evodia rutaecarpa,Coptis chinensis,corrugated,rice bud,Radix Paeoniae Alba,ginger,fennel;the second category:bupleurum,Zhigancao,Clematis;the third category:Pinellia ternata,Pericarpium Citri Reticulatae,Agastache rugosa,jujube,perilla leaf,Magnolia officinalis,Codonopsis pilosula;the fourth category:Astragalus,Platycodon grandiflorum;the fifth category:Poria cocos,Atractylodes macrocephala and Aucklandia.5.Association analysis:using association analysis to classify the association rules of high-frequency traditional Chinese medicine,a total of 25 association rules were obtained.Conclusion:1.To sum up professor Cai Lin’s academic thoughts of spleen and stomach diseases,namely:the spleen and stomach are in harmony,especially Spleen Yang;mediate the rise and fall,so as to stabilize the period;wood and soil are mutually restraining,so as to pay attention to soothing the liver;soil and metal are mutually reinforcing,so as not to forget to ventilate the lung;chronic diseases enter the collaterals,so as to pay attention to removing blood stasis;treating other diseases,we should protect the spleen and stomach.2.Through frequency analysis,it is found that chronic gastritis is easy to occur in middle-aged and elderly people,mostly female patients;It is concluded that Professor Cai Lin’s commonly used traditional Chinese medicines for chronic gastritis are Poria cocos,Atractylodes macrocephala,dangshen,Zhigancao,bupleurum,perilla leaf,Daoya,Pinellia ternata,Magnolia officinalis and Evodia rutaecarpa;the commonly used four Qi and five flavors are mainly pungent and Ganping,and the meridian tropism is mainly spleen,stomach,lung and liver meridians The main effect is tonifying drugs.3.Through cluster analysis and correlation analysis,it is concluded that Professor Cai Lin’s treatment of chronic gastritis is based on the principle of invigorating the spleen and replenishing qi,supplemented by warming the spleen,soothing the liver and relieving depression,removing dampness and invigorating the spleen,and dispersing the lung. |