Study Of The Changes Of Pulmonary Function,Ocular Vascular Hemodynamics And Dark Circles In Bronchial Asthmatic Patients

Objective: To investigate the changes in pulmonary function,ocular vascular hemodynamics,and dark circles in bronchial asthmatic patients and the correlation between the three.Methods: Ninety bronchial asthma patients who attended the outpatient or inpatient department of the Department of Respiratory Medicine of Yueyang Second People’s Hospital from September 2019 to January 2021 and met the inclusion and exclusion criteria were collected as the experimental group,and then divided into experimental group one,experimental group two,and experimental group three according to the persistent severity of asthma;30 healthy physical examiners were selected as the control group during the same period.General data were collected,and pulmonary function was measured using an automatic lung function tester.Color Doppler imaging was used to measure the hemodynamic-related parameters of the ophthalmic artery and central retinal artery,to compare the differences in ocular hemodynamics between the two groups,and to analyze the correlation between pulmonary function and ocular hemodynamics.According to the developed dark circles grading standard,observe the changes of dark circles in bronchial asthma patients,and analyze the correlation between dark circles and ocular hemodynamics and lung function.Results:1.There were no statistically significant differences between the experimental and control groups in terms of gender,age,duration of disease,body mass index,visual acuity,intraocular pressure,family history,and allergy history.2.FEV1,FVC,FEV1/FVC,and FEV1% were higher in the control group than in the experimental group(P < 0.05).3.The PSV,EDV and RI of the ocular vessels in the experimental group were higher than those in the control group,in which the PSV of CRA,RI and PSV of OA in the experimental group were statistically different from those in the control group.4.PSV,EDV,and RI increased with increasing asthma persistence,with statistically significant intergroup differences between the three groups of PSV,RI,and PSV in CRA and OA.5.The results of correlation between pulmonary function and ocular vascular hemodynamics in bronchial asthmatic patients showed that FEV1 and FVC were both negatively correlated with PSV and RI in and OA and CRA(P < 0.05).FEV1/FVC and FEV1% were both negatively correlated with PSV and RI in and CRA and PSV in OA(P < 0.05).6.The percentage of the overall number of patients with high grading of dark circles under the eyes was higher in the experimental group than in the control group(P < 0.05),and the percentage of patients with higher grading of dark circles under the eyes increased as the asthma persistence level increased(P < 0.05).The longer the duration of asthma and the longer the family history and allergy history of asthma patients,the higher the classification of dark circles under the eyes(P < 0.05).7.There was a positive correlation between dark eye grading and PSV and RI of CRA and OA in patients with bronchial asthma(P <0.05).8.The classification of dark circles is negatively correlated with FEV1,FVC,FEV1/FVC and FEV1%(r <0,and P <0.05).Conclusion:1.Bronchial asthma patients may have ocular hemodynamic changes.PSV and CRA with OA manifested as PSV and RI are higher than normal,and their values are positively correlated with asthma persistence grade and dark circles grading,and lung function the indicators are negatively correlated.2.Some bronchial patients with asthma may have dark circles under their eyes,and those with long duration of disease,family history of asthma and allergy,and poor control level of asthma have higher levels of dark circles under their eyes.The level of dark circles is negatively correlated with lung function indicators.