Correlation Analysis Of Glucose And Lipid Metabolism Level And TCM Syndrome Types In Patients With Colorectal Cancer

Objective: Through retrospective research,observe the level of glucose and lipid metabolism in 200 patients with colorectal cancer,analyze the composition ratio of the four groups of patients with abnormal blood glucose,dyslipidemia,abnormal glucose and lipid,and no abnormal glucose and lipid,and explore the relationship between different glucose and lipid metabolism levels and TCM syndrome Relevance.Methods: Retrospective analysis was used to screen 200 newly diagnosed patients with colorectal cancer in strict accordance with the inclusion and exclusion criteria,and focus on monitoring the fasting blood glucose(GLU),triglyceride(TG),and total cholesterol(CHOL)of the patients,High density lipoprotein(HDL-C),low density lipoprotein(LDL-C)levels,statistics of patients with abnormal blood sugar,dyslipidemia,patients with abnormal glucose and lipids,and patients without abnormal glucose and lipids Component ratio: Combining the patient’s symptoms,signs,tongue coating,and pulse conditions for syndrome differentiation,analysis of the correlation between different levels of glucose and lipid metabolism and TCM syndrome types,and analysis of colorectal cancer glucose and lipid metabolism levels and TCM syndrome types in gender,age,The distribution of lesions and TNM stages.Results: 1.Among the 200 patients with colorectal cancer,25 had abnormal blood glucose,accounting for 12.50%;106 had abnormal dyslipidemia,accounting for 53.00%;20 had abnormal glycolipid,accounting for 10.00%;49 had no abnormal glycolipid,accounting for 24.50%.2.Among the 200 patients with colorectal cancer,62 patients had internal accumulation of damp-heat syndrome,accounting for 31.00%,59 patients had internal obstruction syndrome of stasis,accounting for 29.50%,38 patients had spleen and kidney deficiency syndrome,accounting for 19.00%,liver and kidney yin.There were 41 patients with deficiency syndrome,accounting for20.50%.Among them,there were 2 cases of abnormal blood sugar(3.23%)in the syndrome of damp-heat internal accumulation,37 cases of abnormal blood lipids(59.68%),4 cases of abnormal glucose and lipids(6.45%),and 19 cases(30.64%)of no abnormalities in glucose and lipids;There were 17 cases of abnormal blood glucose(28.81%),29 cases of abnormal blood lipids(49.15%),9 cases of abnormal glucose and lipids(15.25%),4 cases of normal glucose and lipids(6.79%);4cases of abnormal blood glucose in the syndrome of spleen and kidney deficiency(10.53%),18 cases(47.37%)with abnormal blood lipids,4 cases(10.53%)with abnormal glucose and lipids,12 cases(31.57%)with no abnormalities in glycolipid;2 cases(4.88%)with abnormal blood glucose in liver and kidney yin deficiency.There were 22 cases(53.66%)with dyslipidemia,3 cases(7.32%)with abnormal glucose and lipids,and 14 cases(34.14%)with no abnormalities in glycolipid.3.Statistics show that there is a statistically significant difference in TCM syndrome between patients with abnormal blood glucose and those without abnormal glucose and lipids(P<0.05).Patients with abnormal blood glucose have the syndrome of stasis and internal obstruction;There is a statistical difference in TCM syndrome types(P<0.05).Patients with abnormal glucose and lipids mainly have the syndrome of blood stasis and internal resistance;patients with dyslipidemia and patients without abnormal glucose and lipids have statistical differences in TCM syndrome types(P<0.05),Patients with dyslipidemia are mainly damp-heat internal accumulation syndrome.4.Among the patients with abnormal blood sugar,there were 5 cases in stage I,stage II,and stage III,each accounting for 20.00%,and 10 cases in stage IV(40.00%).Among the patients with dyslipidemia,there were 10 cases(9.43%)in stage I,20 cases in stage II(18.87%),32 cases in stage III(30.19%),44 cases in stage IV(41.51%);5 cases in stage I(41.51%)in dyslipidemia patients(25.00%),4 cases in stage II(20.00%),1 case in stage III(5.00%),10 cases in stage IV(50.00%);6 cases in stage I(12.24%)in patients with no abnormalities in glycolipid,19 cases in stage II(38.78%);12 cases(24.49%)in stage III and12 cases(24.49%)in stage IV.According to statistical analysis,patients with dyslipidemia and those without abnormal glucose and lipids have statistical significance in TNM staging(P < 0.05).TNM staging of patients with dyslipidemia is mostly in stage IV;patients with abnormal glucose and lipids and patients with no abnormal glucose and lipids are in TNM There was a statistically significant difference in staging(P<0.05).The TNM staging of patients with abnormal glucose and lipids was mostly in stage IV;there was no statistical significance in TNM staging between patients with abnormal blood glucose and those without abnormal glucose and lipids(P>0.05).There was no statistical difference in different levels of glucose and lipid metabolism in gender,age,and lesion location(P>0.05).5.There were statistical differences in age and TNM staging of colorectal cancer in TCM syndrome types(P<0.05),but no statistical differences in gender and lesion location(P>0.05).Among them,the patients under 60 years old mostly have the syndrome of internal accumulation of damp-heat,and the patients over 60 years old have the syndrome of internal obstruction of stasis toxin and the syndrome of liver and kidney yin deficiency.Stage I and II patients mainly have the syndrome of internal accumulation of damp-heat,stage III patients have the syndrome of internal resistance to stasis toxin,and stage IV patients have the syndrome of liver and kidney yin deficiency.Conclusion: Patients with colorectal cancer often have abnormal levels of glucose and lipid metabolism.Patients with abnormal blood glucose and glucose and lipids mainly have the syndrome of internal resistance to blood stasis,and patients with abnormal blood lipids have the syndrome of internal accumulation of damp-heat.Patients with stage IV colorectal cancer are more prone to abnormal changes in the level of glucose and lipid metabolism.In the clinical treatment of patients with abnormal glucose and lipids colorectal cancer,the patient’s body state and stage differentiation should be analyzed according to age,attention should be paid to traditional Chinese medicine care,and the patient’s glucose and lipid metabolism level should be closely monitored.