| Objective: Objective to understand the distribution and correlation of constitution and syndrome types of T2 DM patients,and analyze the correlation between constitution and syndrome types and glucose metabolism index,lipid metabolism index and inflammation index.Objective to explore the application advantages of "constitution differentiation-disease differentiation-syndrome differentiation" diagnosis and treatment mode in the management and prevention of chronic diseases of T2 DM,and to provide TCM theoretical basis for clinical diagnosis and treatment and home management of T2 DM patients.Methods: The subjects were T2 DM patients from Sichuan Hospital of traditional Chinese medicine,Huayang Community and Hongpailou community health service center from January2020 to January 2021.The patients who met the inclusion criteria were investigated by questionnaire to collect relevant information.Results:1.General data analysis: A total of 285 patients with T2 DM were included in the study.The sex ratio was 1:1.05,the average age was 60.51 ± 11.22 years,the average course of disease was 9.68 ± 7.13 years,the average age of onset was 50.84 ± 9.81 years,the average body mass index was 24.52 ± 3.23 kg / m2,and the average waist circumference was 92.29 ± 8.84 cm.2.Constitution analysis of TCM:(1)Yin deficiency(28.1%)> Qi deficiency(19.6%)>phlegm dampness(16.5%)> damp heat(10.5%)> Blood Stasis(8.1%)> Yang deficiency(7.7%)> Qi depression(4.6%)> peace(3.2%)> special nature(1.8%).Due to the small number of cases with peaceful and idiosyncratic qualities,a total of 271 cases of T2 DM patients were finally included in the statistics.(2)Constitution is related to gender,age,course of disease,age of onset,smoking history,drinking history,body mass index,waist circumference(P<0.05).There was no correlation between Constitution and family history,apolipoprotein B,and Creactive protein(P>0.05).(3)The main types of constitution of T2 DM patients are yin deficiency,Qi deficiency,phlegm dampness and damp heat.With the increase of age and the prolongation of the course of disease,the constitution may be transformed into yang deficiency and blood stasis.3.Analysis of TCM syndrome types:(1)Qi Yin deficiency syndrome(26.6%)> kidney yin deficiency syndrome(15.5%)> stomach heat hyperactivity syndrome(12.9%)> blood stasis venation syndrome(12.5%)> lung heat and fluid injury syndrome(11.8%)> dampness heat trapping spleen syndrome(11.5%)> Yin Yang deficiency syndrome(9.2%).(2)The syndrome type was correlated with gender,age,course of disease,smoking history,drinking history,2-hour postprandial blood glucose(P < 0.05).There was no correlation between syndrome type and onset age,family history,fasting blood glucose,cholesterol,triglyceride,apolipoprotein B,C-reactive protein(P > 0.05).(3)In the early stage of the disease,the main syndrome types were stomach heat and dampness heat trapping spleen,while Yin Yang deficiency and blood stasis were the main syndrome types in the later stage of the disease.4.Correlation analysis of constitutions and syndrome type: 271 T2 DM patients were analyzed in constitution and syndrome types.The TCM Constitution of T2 DM patients had a certain tendency in disease syndrome types.Qi deficiency is more common in Qi Yin deficiency syndrome;Yin deficiency is more common in kidney yin deficiency syndrome,Qi Yin deficiency syndrome;Yang deficiency is more common in both yin and yang deficiency syndrome,;Phlegm dampness and damp heat are more common in dampness heat trapping spleen syndrome,lung heat and fluid injury syndrome,stomach heat hyperactivity syndrome;Qi depression and blood stasis are more common in blood stasis syndrome.Conclusion:1.There are certain characteristics in constitution and syndrome types of T2 DM patients,which are correlated with general demographic data,glucose metabolism index and lipid metabolism index,but not with inflammatory index.There is an internal relationship between the distribution of constitution and syndrome types.2.In the stage of obvious symptoms and poor blood glucose control,the patients should be treated according to disease differentiation and syndrome differentiation in medical institutions to reverse their hyperglycemia.Then we can identify the constitution of patients,adjust the constitution of patients through a variety of ways(drug and non drug intervention),extend the hospital treatment to family management and treatment,in order to achieve the goal of reducing blood sugar,lipid,reducing complications and delaying complications,so as to make the " Constitution differentiation-disease differentiation-syndrome differentiation " chronic disease management mode better serve T2 DM patients. |
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