Study On The Distribution And Correlation Of TCM Syndromes Of Peptic Ulcer

Objective: to provide theoretical basis for clinical diagnosis and treatment of peptic ulcer by exploring the distribution of TCM syndromes and analyzing the relationship between related factors and syndromes.Methods: 120 patients with peptic ulcer who met the inclusion criteria in the First Affiliated Hospital of Guangxi University of traditional Chinese medicine from January 2019 to January 2021 were collected.The clinical data observation table was made,investigated and summarized,the database was established,and the data was entered into spss26.0 software for statistical analysis.The distribution of TCM syndromes,gastroscopy results,HP infection,four diagnostic information,treatment and medication of patients with peptic ulcer were described and analyzed.result:1.The distribution of TCM syndromes was as follows: spleen and stomach weakness(36.7%)> stagnation of heat in liver and stomach(19.2%)>disharmony between liver and stomach(14.3%)> damp heat in spleen and stomach(13.3%)> stagnation of stomach collaterals(10.8%)> deficiency of stomach yin(5.8%).2.Occupational distribution: 34 workers(28.3%)> 24 unemployed(20.0%)>22 retired(18.3%)> 17 individuals(14.2%)> 11 staff(9.2%)> 7 farmers(5.8%)> 3 students(2.5%)> 2 teachers(1.7%)3.Gender and age distribution: gender distribution: male: female = 3:1.Age distribution: middle-aged people > old people > young people.There was significant difference in TCM syndromes and gender(P < 0.05),and the proportion of female patients with disharmony between liver and stomach was higher than that of other syndromes;there was no significant difference in TCM syndromes and age(P > 0.05).4.Distribution of smoking and drinking: smoking accounted for 23.3% of all cases,and drinking accounted for 33.3% of all cases.There was no significant difference between TCM syndromes and smoking(P > 0.05).There was significant difference between TCM syndromes and drinking(P < 0.05).The drinking rate of liver stomach heat stagnation syndrome was higher than that of other syndromes.5.HP infection distribution: HP infection rate was 43.3%.The difference between TCM syndromes and HP infection was statistically significant(P <0.05).The HP infection rate of spleen stomach damp heat syndrome was higher than that of other syndromes.6.Endoscopic manifestations: ulcer type: Du 63.3%,Gu 28.3%,Cu 8.3%.DU:GU 2.15:1。 Number of ulcers: 63 cases(52.50%)were single ulcers,57cases(47.5%)were multiple ulcers.Ulcer area: < 0.5cm2 in 78 cases,≥0.5cm2 in 25 cases,≥ 1cm2 in 17 cases.There was no significant difference in TCM syndromes and ulcer type,ulcer number and ulcer area(P > 0.05).7.The four diagnostic information of Pu: epigastric pain(distending pain,dull pain,stabbing pain),anorexia,less Qi and lazy speech,noisy acid regurgitation,dry mouth and bitter mouth,nausea and vomiting,etc.Most of them have red tongue and thin white fur.The pulse condition is mainly deep and thin.8.Distribution of common drugs of Pu: the top ten drugs used were licorice,Atractylodes macrocephala,tangerine peel,Codonopsis pilosula,Paeonia lactiflora,Poria cocos,Angelica sinensis,bupleurum,Pinellia ternata and Cyperus.9.Drugs commonly used in various syndromes: the basic prescriptions of disharmony between liver and stomach are bupleurum,Paeoniae Alba,Cyperus,tangerine peel,licorice,Ligusticum chuanxiong and Fructus aurantii.The basic prescriptions of Gan Wei Yu re were Radix Paeoniae Alba,Radix Bupleuri,Rhizoma Cyperi,Rhizoma Coptidis,Radix Scutellariae,Fructus Gardeniae and Rhizoma Corydalis.The basic prescriptions of spleen stomach damp heat are coix seed,Pinellia ternate,licorice,Coptis,gardenia and poria cocos.The basic prescriptions of spleen and stomach weakness are licorice,Atractylodes macrocephala,Codonopsis,tangerine peel,angelica,astragalus,Pinellia.Radix Codonopsis,Rhizoma Corydalis,Radix Glycyrrhizae,Radix Astragali,Rhizoma Curcumae and Rhizoma Atractylodis Macrocephalae are the basic prescriptions of weiluoyuzu.The basic prescriptions for stomach yin deficiency were Angelica sinensis,Shenqu,hawthorn,Shashen,Raphani seed,polygonatum odoratum and Shengdi.Conclusion1.The main symptoms are epigastric pain,anorexia,lack of Qi,lazy speech,light red tongue,thin white moss and fine pulse.The main symptoms were noisy acid regurgitation,dry mouth,bitter mouth,nausea and vomiting.2.There is a certain internal relationship and regularity between TCM syndromes and gender,drinking,HP infection.3.Men are more likely to suffer from this disease than women,middle-aged and old people are more likely to suffer from this disease than young people.4.The principle of Pu treatment is to strengthen spleen and Qi,soothe liver and stomach.