Study On The Distribution Law Of TCM Syndrome Elements Of Peptic Ulcer And Its Correlation With Gastric Mirror Image

Objective: Investigate the distribution of TCM syndrome for patients with peptic ulce,and conduct observation and analysis after combine with visua pathological manifestations of mucosa under gastroscope,to study the correlation between gastroscopy and PU syndrome from the micro level.Investigate the relationship between gastroscope and peptic ulcer differentiation,provide new insights for objective research on TCM reatment with syndrome differentiation,further deepening the understanding of TCM theory for peptic ulcer,improve the clinical diagnosis level of the disease in some exten.Method: Gather 200 case information of syndromes in patients with peptic ulcer in accord with the demands and gastroscopy record.Switch symptom to syndrome elements by WF-ⅢTCM(auxiliary)diagnosis and treatment system,analyse the regularities of distribution for syndrome elements and correlation between it and gastroscopy.Results:1.The distribution characteristics of syndrome elements for PU: The main syndrome elements of disease location are stomach,liver,spleen,involve small intestine,large intestine,heart;The main syndrome key factors are qi stagnation,deficiency of vital energy,heat,deficiency of yin,damp,involve blood-insufficiency,deficiency of yang,circulation of vital energy in the wrong direction,blood stasis,dyspepsi etc.2.The relationship between PU typing and TCM syndrome: From the distribution characteristics of syndrome elements,the syndrome elements of disease location of 3type for PU have no statistical significance(P>0.05);but regarding syndrome key factors,CU and GU occurs more frequently than DU,The difference between CU and DU is statistically significant(P<0.05);The difference between GU and DU is highly statistically significant(P<0.01);The blood-insufficiency of DU occurs more frequently than GU,the difference is highly statistically significant(P<0.01).Regarding difference of the syndrome integral,different type of deficiency of vital energy,wet syndrome integral difference have statistical significance(P<0.05).The syndrome element integra of qi deficiency in CU is higher than DU and GU(P<0.05).The syndrome element integra of dampness in GU is higher than DU(P<0.05).3.The relationship between PU periodization and syndrome elements: From the frequency distribution of syndrome elements,there are no statistical significance on distribution differences in three stages of PU for syndrome elements(P>0.05);Regarding integral differences of syndrome elements,different stage of deficiency of qi stagnation,deficiency of yin syndrome integral difference have statistical significance(P<0.05);The syndrome element integra of qi stagnation in stage A is higher than stage S(P<0.05).The syndrome element integra of deficiency of yin in stage S is higher than stage H(P<0.05).4.The relationship between gastric mucosal sign and syndrome elements: There are no statistical significance between the microscopic signs of mcosal hyperemi,ulcer area,deformed spherical confinement/pylorus and syndrome element in different distribution of TCM syndrome(P>0.05);The gastroscopic signs of mucosal edema is evident with heat and dampness syndrome element,and had statistical significance compared with others(P<0.05).The gastroscopic signs of mucosal erosion is evident with qi stagnation,heat and blood stasis syndrome element,and had statistical significance compared with qi deficiency,dampness,yang deficiency,qi inversion and phlegm(P<0.05).The gastroscopy signs of mucosal hemorrhage is evident with motile blood,blood deficiency and blood stasis syndrome element.Compared with qi stagnation,heat,yin deficiency,dampness,inverses of qi,food accumulation and phlegm,the syndrome element of blood deficiency have more statistically significance(P<0.05).Blood stasis syndrome element have more statistical significance than qi stagnation,heat,yin deficiency,inverses of qi(P<0.05).The ulcer attached to the moss was white,mostly found in deficiency of vital energy,blood deficiency and yang deficiency,have more statistical significance than food accumulation and phlegm(P<0.05),have highly statistically significant than heat and dampness(P<0.01).The ulcer attached to the moss was yellow,mostly found in syndrome elements of heat,dampness,food accumulation and phlegm,compared with qi deficiency,deficiency of blood and yang deficiency,syndrome elements of heat,dampness have highly statistically significant(P<0.01),compared with qi deficiency,blood deficiency and yang deficiency,syndrome elements of food accumulation and phlegm have more statistical significance(P<0.05).Conclusion:The main syndrome elements of disease location of the PU are stomach,liver and spleen;and the main solid syndrome key factors are qi stagnation,heat,damp,circulation of vital energy in the wrong direction,blood stasis,virtual syndrome key factors are deficiency of vital energy,deficiency of Yin,blood-insufficiency,deficiency of yang.DU is the most common of the three PU typing,what’s more,blood deficiency syndrome is more likely to occur in DU.GU is more closely related to the syndrome elements of phlegm,the correlation is more significant between CU and deficiency of vital energy,the stage A of PU disease is mainly the real.qi stagnation have the most degree of pathology,the stage S of PU disease is mainly the virtual,deficiency of Yin have the most degree of pathology.There is a certain internal connection and regularity betweem endoscopic mucosal signs and TCM syndrome for PU,the introduction of gastroscope to TCM syndrome differentiation is helpful for the clinical diagnosis and objective research of the disease.