The Clinical Study Of Qingfei Huatan Decoction In Treating Phlegm-heat Obstructing Lung Syndrome Of Non-severe Senile Pneumonia

Objective:To evaluate the clinical efficacy and safety of Qingfei Huatan Decoction in treating phlegm-heat obstructing lung syndrome of non-severe senile pneumonia.This project compares the differences in test indicators,symptoms and signs,lung CT imaging scores,and duration of hospital stays between the control group and the treatment group.Methods:The non-severe senile pneumonia patients who enrolled in this research were divided into control group(n=30)and treatment group(n=30)at random.Observation of indicators:white blood cells,the neutrophil ratio,hypersensitive C-reactive protein in the blood were assessed before treating and on the 4th,7th day of treatment.PCT,albumin,AST,ALT,serum creatinine,blood urea,T lymphocyte subsets were examined once before and after treatment.Compared the scores of TCM syndrome,symptom and sign scores at the points before treatment and the 3rd,5th and 7th day of treatment.At the same time,the antipyretic time and Duration of hospital stay were recorded.CT Scan of the Lung was rechecked in day 14 after treatment.And then all the statistical data were collated and analyzed.Results:1.The basic data of two groups are comparable(P>0.05).2.WBC,N%,hs-CRP:Comparison between groups show statistically significant differences on the 4th day of treatment(P<0.05),which is lower in the treatment group;On the 7th day of treatment,the distinction is statistically significant(P<0.01),the treatment group reduce obviously contrasted with the control group.Within groups,the differences on the 4th and 7th day after treatment are statistically significant compared with those before treatment(P<0.01).3.PCT:There is no statistical significance between the two groups(P>0.05).At the end of the treatment,the results reach statistical significance(P<0.01).3.Albumin:The two groups have no statistically significant differences before treating(P>0.05).Intra-group comparison,there is no statistical significance in the control group(P>0.05),in contrast,the change in the treatment group has significant statistical significance(P<0.01).4.CD3+,CD4+/CD8+:There is no statistical significance between groups before treatment(P>0.05);After treatment,the difference has statistically significant(P<0.05),which is higher in treatment group.Intra-group comparison,although the control group has no statistical significance before and after treating(P>0.05),there is significant statistical significance in treatment group(P<0.01).5.Symptoms and signs:There is statistical significance on the 5th day of treatment(P<0.05),and is notable statistical significance on the 7th day of treatment(P<0.01)6.Lung CT:By comparing the results of the two groups,it shows that there is no statistically significant difference before treating(P>0.05),but is statistically significant improvement after treatment(P<0.05).intra-group comparison shows that there is significant statistical differences between the two groups before and after treatment(P<0.01),and both are improved after treatment.8.fever clearance time and days of hospital stay:Both groups’ fever clearance time has no statistical significance(P>0.05).The days of hospital stay in the treatment group is shorter than control group,and the result is statistically significant(P<0.05).9.Evaluation of the therapeutic efficiency:The total effective rate of the two groups is 100%.The treatment group was superior to the control group in terms of clinical control rate and significant efficiency.10.Security index:There is no statistical significance(P<0.05).Conclusion:1.Qingfei Huatan Decoction combined with Western medicine in the treatment of non-severe senile pneumonia with phlegm-heat obturation of the lung syndrome has a positive effect in reducing inflammatory indexes,regulating the immune function of the body,improving nutritional status and absorption of lesions.2.Qingfei Huatan Decoction can improve the symptoms and signs of patients with non-severe senile pneumonia with phlegm-heat obturation of the lung syndrome,at the same time it can reduce complications and shorten the duration of hospital stay.3.Qing Fei Hua Tan prescription is not found to cause liver and kidney toxicity,so it is safe to use.