Study On Professor Guo Lizhong’s Medical Record Within Treating Chronic Glomerulonephritis From Assisting Yang

ObjectiveDiscuss the treating methods and prescription characristics from professor GuoLiZhong’s medical redcord within treating chronic glomerulonephritis from assisting Yang during recent 5 years by using computer data mining technology.MethodGather all of professor guolizhong’s medical records into"medcase v3.2"software during january 2016 to december 2020.Screen these records by particular rules and standardlize them,then analysis them for statistics,such as frequency data and association items,by using the following softwares:Excel2013;SPSS25.0;a low code development platform based on Delphi language.ResultsThroughout the 375 chosen medical redcords from 58 visitors including 19 men(33%)and 39 women(67%),the youngest is 14 years old while the oldest is 77.The majority of visitor’s age ranges between 30 and 59(67.25%),which indicates the visitors are middle-aged.Frequency:Clinical symptoms amounts to 214 kinds,top 10 are fatigue(42%);poor sleep(38%);soreness of waist(32%);nocturia(26%);urine foam(24%);hyperhidrosis(23%);edema of limbs(23%);thirst(19%);dream-disturbed(18%);feeling cold(17%)in sequence.Tongue features amounts to 47 kinds,top 5 are white-thin tongue coat(37%);light-red tongue(29%);tooth mark(26%);light-color tongue(22%);white-greasy tongue coat(1 7%)in sequence.Pulse features amounts to 24 kinds,top 3 are fluent pulse(39%);slender pulse(35%);weak pulse in chi-position(25%).Pathogenesises amounts to 69 kinds,top 10 are Yang and essence’s deficiency(23%);spleen Yang and kidney Yang’s deficiency(14%);spirit lacking blood’s nurture(13%);heart and spleen’s deficiency(10%);cold and wetness blocking in the middle jiao(9%);cold and wetness’s stagnation(9%);Yang and qi’s deficiency(9%);kidney unable governing(7%);kidney unable transpiring water(6%);kidney Yang’s deficiency down below(5%)in sequence.Medicines amounts to 148 kinds,top 10 are roasted licorice(88%);amomum villosum(86%);processed monkshood(79%);raw atractylodes macrocephala(75%);epimedium(74%);ginger(71%);raw astragalus(53%);poria with hostwood and mixed cinnabar(50%);ramulus cinnamomi(45%);codonopsis pilosula(41%)in sequence.Association:Highly relevant association from clinical symptoms to pulse features are:edema of limbs/urine foam/hyperhidrosis→weak pulse;nocturia/thirst→fluent pulse.Highly relevant association from clinical symptoms to tongue features are:fifteen common clinical symptoms→light-color tongue.Highly relevant association from clinical symptoms to pathogenesis are:soreness of waist→Yang and essence’s deficiency;yellow urine→kidney unable governing;gastric distension→spleen Yang and kidney Yang’s deficiency;poor appetite→spleen Yang and kidney Yang’s deficiency/cold and wetness blocking in the middle jiao.Highly relevant association from tongue features to pathogenesis are:red tongue/dark tongue/white tongue coat→Yang and essence’s deficiency.Highly relevant association from pulse features to pathogenesis are:slender pulse/tight pulse/wiry pulse/feeble pulse→Yang and essence’s deficiency.Highly relevant association from clinical symptoms to medicines are:thirst/dream-disturbed→roasted licorice;feeling cold/edema of limbs/diarrhea→amomum villosum.Highly relevant association from pathogenesis to medicines are combined as follows.Cold and Wetness’s stagnation causing Qi and Blood running unsmoothly/pathogenic factors hiding in TaiYang Channel,causing incoordination between nutrient Qi and defensive Qi→ramulus cinnamomi,roasted licorice,ginger,chinese atractylodes,poria with hostwood and mixed cinnabar,amomum villosum,acorus tatarinowii,etc;Spleen Yang and Kidney Yang’s deficiency causing Cold and Wetness blocking in the middle Jiao→cardamom,amomum villosum,processed monkshood,raw atractylodes macrocephala,poria with hostwood and mixed cinnabar,ramulus cinnamomi,roasted licorice,etc;Heart and Spleen’s deficiency causing Spirit lacking Blood’s nurture→raw astragalus,raw atractylodes macrocephala,roasted licorice,poria with hostwood,amomum villosum,polygala root,fried semen ziziphi spinosae,etc;Yang and Essence’s deficiency/Yang and Qi’s deficiency,causing Kidney unable to govern→processed monkshood,codonopsis pilosula,raw astragalus,raw atractylodes macrocephala,roasted licorice,the seed of chinese dodder,epimedium,morinda officinalis,amomum villosum,etc;Kidney Yang’s deficiency down below,causing Kidney unable transpiring Water,therefore Water stops flowing→processed mookshood,poria cocos,raw atractylodes macrocephala,ginger,epimedium,amomum villosum,ramulus cinnamomi,etc;Kidney Yang’s deficiency down below,causing Yin-fire rising and Kidney-Heart disharmony→phellodendron amurense,amomum villosum,roasted licorice,anemarrhena asphodeloides,cinnamon,processed mookshood,epimedium,oroxylum seed,poria with hostwood and mixed cinnabar,fried semen ziziphi spinosae,etc.ConclusionsThrough the research above,combined with opinions from professor GuoLiZhong and the Tutor,the following conclusions are drawn:1.Most of the chronic glomerular nephritis patients which Professor Guo Lizhong treated from assisting Yang are middle-aged women.2.The basic clinical symptoms of those patients are:edema of limbs,urine foam,soreness of waist,fatigue,feeling cold,hyperhidrosis,thirst,poor sleep with dream-disturbing,nocturia;light-color tongue with tooth mark and white-greasy tongue coat;fluent and slender pulse,but weak in chi-position.3.Common pathogenesises of those patients and corresponding therapies for them are:Cold and Wetness’s stagnation causing Qi and Blood running unsmoothly/pathogenic factors hiding in TaiYang Channel,causing incoordination between nutrient Qi and defensive Qi→ingredient-altered GuiZhi decoction and ErChen decoction.Spleen Yang and Kidney Yang’s deficiency causing Cold and Wetness blocking in the middle Jiao→ingredient-altered DingKouLiZhong decoction.Heart and Spleen’s deficiency causing Spirit lacking Blood’s nurture→ingredient-altered GuiPi decoction and SiNi decoction.Yang and Essence’s deficiency/Yang and Qi’s deficiency,causing kidney unable to govern→self-designed"fuYangtianjing" decoction.Kidney Yang’s deficiency down below,causing Kidney unable transpiring Water,therefore Water stops flowing→ingredient-altered ZhenWu decoction.Kidney Yang’s deficiency down below.causing Yin-fire rising and Kidney-Heart disharmony→ingredient-altered FengSui pill and ZiShenTongGuan pill.