Study On The Characteristics Of Dominant Populations With The Spleen-Enriching Qi Method In The Treatment Of Functional Dyspepsia

ObjectiveTo explore the characteristics of the spleen-enriching qi method in the treatment of functional dyspepsia and provide clinical support for precise and individualized treatment of traditional Chinese medicineMethodsThe basic information such as the age and BMI of patients with functional dyspepsia,and clinical information such as syndrome classification and TCM constitutional classification are used to conduct questionnaire surveys in outpatient and ward,and compare the changes in the symptom score of patients before and after treatment to distinguish the dominant group.The data of EpiData(v4.6)was used to establish the efficacy database of spleen-enriching qi for treating functional dyspepsia.SPSS 25.0 statistical software was used for data statistics to clarify the basic characteristics of the dominant population.The measurement data meets the normality test and the homogeneity of variance is selected using the analysis of variance.If it is not satisfied,the non-parametric rank sum test is used;the count data is used the chi-square test;the grade data is used the non-parametric rank sum test.At the same time,data models such as GBDT,XgBboost,and random forest were established for selected indicators through Python 3.6 and the characteristics of the dominant population were analyzed.ResultsA total of 193 patients with functional dyspepsia were included in this study,including 104 predominant populations and 89 non-dominant populations.Analysis of general information:143 cases were included in the outpatient department,50 cases were included in the inpatient department,72 were male,accounting for 37.71%,and 121 were female,accounting for 62.69%.The age distribution ranged from 22 to 85,with an average age of 50.47±14.25 years,with the largest number of patients in the 40-49 age group.The average BMI is 21.45±2.95.Patients with normal BMI account for 66%of the total population.Occupation is mainly in the tertiary industry,accounting for 90.7%,and work status is mainly stable,accounting for 52.8%.57.5%of patients have the habit of daily exercise.The proportion of patients who smoke is 13%and the proportion of patients who drink alcohol is 11.4%.Clinical data:The diagnosis distribution of clinical TCM syndrome types is as follows:spleen deficiency and qi stagnation syndrome>spleen and stomach deficiency syndrome>spleen and stomach dampness and heat syndrome>cold and heat mixed syndrome)liver and stomach discord syndrome,the proportions of which are 65.3%,17.1%,5.7%,1.6%,0.5%;Qi deficiency syndrome has the highest frequency,reaching 100%,followed by Qi stagnation syndrome at 99%,and Yang deficiency syndrome at 20.2%;fatigue are the most frequent symptoms,accounting for 87.6%.The most frequent tongue image was pale tongue,accounting for 89.1%,the highest frequency of tongue coating was thin coating,accounting for 93.8%,and the weakest pulse frequency was highest,accounting for 89.1%.58.5%of patients had a previous medical history,30.1%of patients had surgery,18.7%of patients had a history of allergies,Hp-positive patients accounted for 14.5%,14%of patients were anxious,52.8%of patients were depressive,and yang deficiency Physical appearance frequency was the highest,accounting for 87%,followed by Qi deficiency,accounting for 43%.FDQOL daily activity average score was 71.3±11.9,FDQOL worry average score was 40.9±13.6,FDQOL diet average score was 58.1±13.3,FDQOL sleep average score was 74.5±11.3,the average score of FDQOL discomfort was 77.7± 8.1,the average score of FDQOL disease treatment was 59.5±10.9,the average score of FDQOL disease control was 56.4±15.4,and the average score of FDQOL stress was 66.6±21.2.Characteristics of the dominant population:The difference between the dominant population and the non-dominant population is statistically significant.The source of the dominant population is mainly outpatients,and in terms of age distribution,the dominant population is mainly young and middle-aged patients less than 60.And the BMI of the dominant population,most of them are within the normal range,and are mostly engaged in related work in the tertiary industry.Most of the patients in the advantage group have no history of allergies(87.5%),and the patients in the advantage group are more patients with no anxiety and depression,and their clinical symptoms are mild(94.2%).Modeling results:The performance characterization indexes MSE of GBDT,random forest,and XgBoost are 57.3,52.5,and 79.7,respectively.The Random Forest model has the highest accuracy.ConclusionThe characteristics of the dominant population are that the patients come from outpatient clinics,aged<60 years,normal BMI,engaged in tertiary industry related work and stable working conditions,no history of allergies,SAS score<50,TCM symptom score ≤10,FDQOL daily activities,disease control The score is≥60,the FDQOL anxiety score is<20,the FDQOL diet score is 60-79,and the FDQOL disease treatment score is 40-59;the random forest model has the highest accuracy.Based on the results,the most characteristic indicators of the dominant population are FDQOL anxiety score and TCM symptom score,FDQOL diet score.