Clinical Observation Of Tongfengling Decoction In The Treatment Of Acute Gouty Arthritis With Damp Heat Accumulation

ObjectiveTo observe the clinical effect of Tongfengling Decoction in the treatment of acute gouty arthritis with damp heat accumulation,and to provide the basis for its clinical application.Methods70 cases of acute gouty arthritis were selected from the Department of orthopedics and traumatology of Zhangzhou Hospital of traditional Chinese Medicine Affiliated to Fujian University of traditional Chinese medicine from December 2018 to December2019.Thirty five patients were randomly divided into two groups: the control group was given celecoxib capsule(200mg once a day)and the experimental group was given celecoxib capsule(200mg once a day)+ Tongfengling Decoction(1 dose per day).To evaluate the TCM syndrome score,VAS score,curative effect evaluation,ESR,CRP and UA of the patients on the 2nd,4th and 7th day of treatment,collect data for statistical analysis and record the adverse reactions in the research process,and make scientific curative effect evaluation combined with statistical analysis.Result1.VAS score: comparison between groups: there was no statistical significance(P> 0.05)in the comparison of VAS score before treatment between the two groups,which was comparable;there was no statistical significance(P > 0.05)in the two groups on the 2nd day after treatment,and there was statistical significance(P < 0.01)in the comparison of VAS score on the 4th and 7th day after treatment between the two groups.Intra group comparison: the difference between the two groups after treatm ent and before treatment was statistically significant(P < 0.01).2.UA,ESR,CRP: comparison between the two groups: there was no statistical significance(P > 0.05)between the levels of UA,ESR,CRP before treatment,with comparability;there was statistical significance between the levels of UA,ESR,CRP after treatment in the two groups(P < 0.01).In group comparison: after treatment,UA,ESR and CRP levels of the two groups were statistically significant(P < 0.01).3.TCM symptom score: comparison between groups: there was no significant difference in TCM symptom score before treatment between the two groups(P > 0.05),which was comparable;there was significant difference in TCM symptom score after treatment between the two groups(P < 0.01).Comparison within the group: the difference between the two groups after treatment and before treatment was statistically significant(P < 0.01).4.The results of TCM syndrome analysis: the control group: clinical control 0 cases(0%),significant effect 1 case(2.86%),effective 26 cases(74.29%),ineffective 8cases(22.88%),total effective rate(77.14%).In the treatment group,clinical control was 0 case(0%),significant effect in 4 cases(11.76%),effective in 28 cases(82.35%),ineffective in 2 cases(5.88%),and the total effective rate was 94.12%.There was a significant difference(P < 0.05)between the two groups after treatment.5.Analysis of the total clinical efficacy: the control group: clinical control 0 cases(0%),significant 5 cases(14.29%),effective 25 cases(71.43%),ineffective 5 cases (14.29%),the total effective rate is(85.71%).In the treatment group,clinical control was 0 case(0%),significant effect was 12 cases(35.29%),effective in 21 cases(67.74%),ineffective in 1 case(2.94%),and the total effective rate was 97.06%.There was a significant difference between the two groups(P < 0.05),which was statistically significant.The total effective rate of the experimental group was higher than that of the control group.ConclusionTongfengling decoction combined with celecoxib capsule can effectively improve the clinical symptoms of acute gouty arthritis with damp heat accumulation,which is better than celecoxib capsule alone.