Observation On Clinical Effect Of TCM Plaster On Acupoints And Non-acupoints In Treating Insomnia With Deficiency Syndrome

Objective:By comparing the clinical effects of traditional Chinese medicine application on meridian points and non-acupoints in the treatment of insomnia of deficiency syndrome,the differences of PSQI score,sleep structure and quality of life between the two groups were observed,and the important value of meridian points in the application of traditional Chinese medicine was demonstrated.Method:Seventy insomniacs who met the inclusion criteria were randomly divided into treatment group and control group,35 cases in each group.Selected PSQI scale score,sleep monitoring and quality of life of insomnia Chinese medicine scale score as evaluation indexes.Both groups were treated with traditional Chinese medicine application intervention.The treatment group applied at Shenque,Guanyuan and Zusanli,while the control group treated with 1 acupoint beside the acupoints.Non-acupoint points were selected to apply once every other day for 8 weeks.Before treatment,in the middle period of intervention(4th week),at the end of intervention(8th week),and at the follow-up(12th week),the two groups were scored with the scale.Used SPSS24.0 soft for statistical analysis.Result:1 BaselineIn this study,70 cases of insomnia with deficiency syndrome were included,and 5 cases fell off during treatment.The baseline before intervention showed that there was no distinct difference in age,sex,course of disease,PSQI scale,sleep monitoring data,and the score of Chinese medicine quality of life scale for Insomnia between acupoint group and non-acupoint group before admission(P>0.05),which was comparable.2 Overall efficacyThe effective rate of acupoint group was 75.7%,and that of non-acupoint group was40.6%,P < 0.05,suggesting that the overall effect of acupoint group was better than that of non-acupoint group.3 Main Indicators--PSQI Scale3.1 Intra-group comparison:As for the total score of PSQI scale,compared with that before treatment,the total score of PSQI scale in the two groups decreased after 4 weeks and 8 weeks of treatment,and there was distinct difference between the meridian group and the non-acupoint group at 4 weeks and 8 weeks of treatment(P<0.05),while there was distinct difference between the non-acupoint group and the non-acupoint group at 8 weeks of treatment(P<0.05).In terms of PSQI score,after 8 weeks of treatment,compared with before treatment,6 single scores such as sleep quality in acupoint group were improved,and 5 single scores such as sleep disorder in non-acupoint group were also improved,with statistical significance(P<0.05).3.2 Intergroup comparisonIn terms of total scores of PSQI scale,there were distinct differences between the two groups at 4 and 8 weeks of treatment(P<0.05);in terms of sub-item scores of PSQI scale,there were distinct differences between meridian-acupoint group and non-acupoint group in four dimensions of sleep time,sleep quality,daytime dysfunction and sleep disorder after 8weeks of treatment(P<0.05).Four secondary indicators4.1 sleep structureCompared with the non-acupoint group,the proportion of deep sleep,shallow sleep and REM in the acupoint group increased distinctly(P<0.05).In addition,the proportion of REM in the acupoint group increased distinctly(P<0.05).Compared with the non-acupoint group,the improvement of the proportion of deep sleep,shallow sleep and REM in the acupoint group was better than that in the non-acupoint group,and the difference was statistically distinct(P<0.05).4.2 Insomnia Chinese Medicine Quality of Life ScaleIntra-group comparison: the scores of TCM Quality of Life Scale of Insomnia in acupoint group were lower than those before treatment at 4 weeks and 8 weeks of treatment,and the differences were statistically distinct(P<0.05);the scores of non-acupoint group were distinctly different only at 8 weeks of treatment compared with those before treatment(P<0.05).Inter-group comparison: There were statistical differences between acupoint groupand non-acupoint group in the integral group of TCM Quality of Life Scale for insomnia at 4and 8 weeks of treatment(P<0.05).5 Follow-upThere was no distinct difference in PSQI score between the two groups at follow-up(P>0.05),and there was distinct difference between the two groups at follow-up(P<0.05).6 Safety evaluationIn terms of safety evaluation,the safety of the two groups was better,and no serious adverse events occurred.There was no distinct difference between the meridian group and the non-acupoint group(P<0.05).Conclusion:1.Traditional Chinese medicine application is safe,effective and feasible in treating insomnia of deficiency syndrome.2.Applying meridians and acupoints has faster onset,shorter course of treatment and better curative effect,and has obvious effects in four dimensions: sleeping time,sleep disorder,sleep quality and daytime dysfunction.3.Applying acupoints can improve sleep structure and quality of life of insomnia patients with deficiency syndrome more effectively.