| ObjectiveTo observe the effect of three-needle warm acupuncture therapy on early diabetic lower extremity atherosclerotic disease(DLEAD),to explore the efficacy and safety of this therapy in the treatment of this disease,and to provide safe and effective prevention and treatment of early diabetic lower extremity atherosclerotic disease.MethodsIn this study,prospective randomized controlled clinical trials were used to select 70 patients with DLEAD who met the relevant diagnostic criteria,inclusion and exclusion criteria,and were divided into trial and control groups by 35 patients.The control group used basic treatment(health education,drug hypoglycemic,lipid-regulating stable spots,etc.).The experimental group applied warm acupuncture to the control group,and selected three needles(Zusanli,Sanyinjiao,Neiguan)as the main point alternate temperature.Acupuncture,3 times a week,4 weeks for a course of treatment,a total of 3 courses.The clinical symptoms,laboratory test indicators,quality of life type scale score(DMQLS)of type 2 diabetes,adverse reactions and adverse events were recorded before and after treatment,and the database was established for data management using clinical data.SPSS 21 was used.The 21.0 statistical software package performs statistical processing.Measurement data that conformed to the normal distribution were analyzed by independent samples/tests;The non-normal distribution data is non-parametric test;the small sample(n<50)constitutes the ratio and grade data,and the four-grid table data uses the chi-square test.Results70 patients were enrolled in the study.One patient withdrew from the trial and 7 patients fell off.In the end,62 patients were included in the trial,and 31 patients in the control group and the experimental group.General data such as age,gender,course of disease,comorbidity,TCM type,and academic level of the two groups before treatment,fasting blood glucose(FBG),body mass index(BMI),type 2 diabetes quality of life scale(DMQLS),There were no significant differences in the scores of TCM symptoms(P>0.05),which were comparable.After 3 courses of treatment,the FBG levels in the two groups were significantly lower than those before treatment(P<0.05),and the FBG level in the experimental group was significantly lower than that in the control group.The difference was statistically significant(P<0.05),There were no significant differences in BMI levels between the two groups before and after treatment(P>0.05).It is indicated that both interventions can effectively reduce fasting blood glucose in patients with DLEAD,and combined with warm acupuncture is better than basic treatment alone,but the improvement of BMI level is not obvious in both groups.The scores of the five dimensions of the DMQLS scale after treatment were higher than those before treatment.The difference between the disease dimension and physiological dimension of the control group was statistically significant(P<0.05),social dimension,psychological dimension,There was no significant difference in the satisfaction of treatment before and after treatment(P>0.05).The differences in disease dimension,physiological dimension,psychological dimension and satisfaction between the experimental group and the pre-treatment group were statistically significant(P<0.05),social dimension.The difference was not statistically significant.After treatment,the disease,physiological and satisfaction scores of the experimental group were significantly higher than the control group(P<0.05);there was no significant difference between the social dimension and the psychological dimension score(P>0.05).It shows that basic treatment and warm acupuncture treatment can effectively improve the disease dimension and physiological dimension score of DLEAD patients’ quality of life.Warm acupuncture treatment can also improve patients’ psychological dimension and satisfaction,and the curative effect on disease dimension,physiological dimension and satisfaction is excellent.In simple basic treatment.However,there was no significant difference between the psychological dimension of warm acupuncture treatment and the basic treatment.The treatment of both groups had no obvious effect on the social dimension.After treatment,the total scores of TCM symptoms in the two groups were significantly lower than those before treatment(P<0.05),and the total score of TCM symptoms in the experimental group was significantly lower than that in the control group(P<0.05).After treatment,the test group recovered 0 cases,markedly effective in 14 cases,effective in 15 cases,and ineffective in 2 cases;in the control group,0 cases were cured,3 cases were markedly effective,19 cases were effective,and 9 cases were ineffective.The overall effective rate of the test group was 93.5%,while the overall effective rate of the control group was 71.0%.There was a significant difference between the two groups(P<0.05).There was no significant difference between the two groups in the test group(P>0.05).It indicated that the clinical symptoms of the experimental group improved significantly better than the control group,indicating that the early intervention of combined warm acupuncture can effectively improve the symptoms of discomfort in DLEAD patients with qi and yin deficiency,skin dystrophic syndrome,qi deficiency and blood stasis,and collateral block syndrome.And the effect is better than the basic treatment.After treatment,the numbness,pain and arterial pulsation scores of the control group were significantly lower than those before treatment(P<0.05).There was no significant difference in skin color,skin temperature,intermittent claudication and hair score(P>0.05).After treatment,numbness,pain,skin temperature,intermittent claudication,and arterial pulsation scores were significantly lower than before(P<0.05),and there was no significant difference in skin color and hair score(P>0.05).Compared with the control group,the numbness,pain and skin temperature of the experimental group were significantly decreased(P<0.05).There was no significant difference in pain,skin color,intermittent claudication,arterial pulsation and hair score(P>0.05).It shows that simple basic treatment and warm acupuncture can significantly improve limb numbness,pain and foot artery pulsation,and combined warm acupuncture intervention can improve the numbness and pain of limbs more effectively,and can effectively improve skin temperature and intermittent claudication.The basic treatment has poor curative effect on skin temperature and intermittent claudication.Both treatments have poor curative effect on skin color and hair.Adverse reactions:During the whole test,the main adverse reactions were hypoglycemia and gastrointestinal reactions.One patient in the control group withdrew from the trial due to multiple hypoglycemia reactions.In both groups,there was a case of gastrointestinal dysfunction caused by abdominal distension and anorexia.Considering the side effects of hypoglycemic drugs,the symptoms of discomfort after the adjustment of the drug were alleviated.No other side effects and adverse reactions occurred in the treatment of the remaining patients.The incidence of adverse reactions was 6.5%,and the incidence of adverse reactions in the test group was 3.2%.There was no significant difference between the two groups(P>0.05).ConclusionLipid three-needle warm acupuncture combined with basic therapy can effectively improve fasting blood glucose levels in patients with DLEAD,help to improve glucose metabolism disorders,and can alleviate the clinical symptoms of early DLEAD patients,especially for limb numbness,pain,limb cold,and dorsal artery pulsation Significantly,superior to basic treatment alone,can improve the quality of life of patients,safe and effective,and worth promoting. |
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