Clinical Observation On Treatment Of Perimenopasual Syndrome With Chaihu Longgu Muli Decoction

Objective:This study by observing the Chaihu jia Longgu oyster decoction treating perimenopausal syndrome clinical efficacy,to explore the diagnosis and treatment of Chaihu jia Longgu oyster Decoction mechanism of perimenopausal syndrome,provide safe and effective for clinical treatment of perimenopausal syndrome of drug use.Methods:According to the individual wishes of patients,60 cases of perimenopausal syndrome patients were divided into Chinese medicine group and blank control group 30 cases each.The Chinese medicine group took Chaihu plus Longgu oyster soup,the blank control group did not give any drug treatment,continuous observation of two groups of patients At 4 weeks,8 weeks,and 12 weeks after treatment,changes in Kupperman scores,changes in individual symptoms,and clinical effectiveness,and changes in the four dimensions of the quality of life table before and after treatment in both groups of patients were improved.Results:(1)There was a significant difference in total Kupperman scores before and after treatment in the Chinese medicine group(P<0.05).There was no significant difference in the Kupperman total score between the two groups before and after treatment(P>0.05).There was significant difference in KMI scores between the two groups after treatment(P<0.05);Single symptom score:Chinese medicine group had no obvious effect on the improvement of bone and joint pain,sexual difficulties,urinary tract infection and other symptoms(P>0.05).The control group was divided into two groups:emotional and depressive.Natural remission can be achieved(P<0.05),and no significant improvement was found in other items(P>0.05).(2)After 4 weeks of treatment in the Chinese medicine group,2 cases were cured,10 cases were markedly effective,11 cases were effective,7 were ineffective,and the clinical effective rate was 76.67%.After 4 weeks in the control group,only 1 case was effective,29 cases were ineffective,and the clinical effective rate was 3.33 After 8 weeks of treatment in the Chinese medicine group,4 cases were cured,12 cases were markedly effective,10 cases were effective,4 cases were ineffective,and the clinical effective rate was 86.67%.After 8 weeks of treatment in the control group,4 cases were effective,and 26 cases were ineffective.Clinical efficiency 13.33%;After 12 weeks of treatment in the Chinese medicine group,4 cases were cured,15 cases were markedly effective,9 cases were effective,2 cases were ineffective,and the clinical effective rate was 93.33%.After 12 weeks of treatment in the control group,6 cases were effective and 24 cases were ineffective.The effective rate is 20.00%;(3)The vasomotor dilatation dimension,psychological dimension and physiological dimension of Chinese medicine group were lower than those before treatment,and the difference was statistically significant(P<0.05).The sex life dimension was not significantly improved before treatment,and the difference was not statistically significant(P>0.05);the control group only improved in the psychological dimension.Conclusion:Chaihu jia Longgu oyster decoction is a safe and effective treatment for perimenopausal syndrome.