Clinical Research On Acupuncture And Pricking Therapy Combined With Moxibustion For The Treatment Of Liver-stagnation And Spleen-deficiency Syndrome Of Depressive Neurosis

ObjectiveTo estimate the clinical efficacy of acupuncture and pricking therapy combined with moxibustion for the treatment of liver-stagnation and spleen-deficiency syndrome of depressive neurosis,in order to explore an effective treatment with the character of Traditional Chinese Medicine,and has no side effects.MethodsRandomly divide the 66 patients of liver stagnation and spleen deficiency syndrome of depressive neurosis who are in compliance with the standard.(Produce random number with Excel).Divide the research subject into two group.One group was treated with acupuncture and pricking therapy combined with moxibustion(APM group).The control group was treated with acupuncture and pricking therapy(AP group).There are six shedding cases and 30 actual effective cases respectively for each group.The AP group use acupuncture and pricking therapy.Acupuncture prescription:Siguan points(Taichong,hegu),Baihui acupoint,ophryon(refer to Wenbin Fu,Li Fan,Xiaoping Zhu.Clinical study on using liver-function-regulating method to treat depressive neurosis[J].2006,31(6):355-358.)Acupoint selection for pricking therapy:The first pair choose Geshu point;the second pair choose Ganshu point.Both have bilateral sides.Select one pair each time and use it alternatively in two groups.The APM group use acupuncture and pricking therapy combined with moxibustion,and the way of acupuncture and pricking therapy refer to the AP group.Moxibustion takes Shenjue as the center and insert the acupuncture needle at the same time.Put the moxa box at the abdomen,covering the acupoints such as shenque,zhongwan,xiawan,qihai and guanyuan.Treatments of both groups were required in every three days to ensure two treatments per week.Two weeks were a course,and the treatment courses lasted 4 weeks.Conduct SDS assessment and HAMD assessment and TCM syndrome assessment for the patients in two groups respectively at pre-operation,two weeks after treatment and four weeks after treatment.Evaluate therapeutic effect after two weeks treatment and four weeks treatment.Results1.Comparision of baseline dateTwo groups of patients had no significant difference(P>0.05)in age,gender,SDS score,HAMD score and score of TCM syndrome,which means they were comparable.2.Comparision of observation indexes(1)Comparision of SDS assessment scoreAfter t examination,①two weeks after treatment:the APM group decreased in its assessment score compared with pre-treatment,and there is statistical significance(P<0.01);the AP group decreased in its assessment score compared with pre-treatment,and there is statistical significance(P<0.01);Compare with the assessment score between the two groups,there is no statistical significance(P>0.05);②four weeks after treatment,the APM group decreased in its assessment score compared with that of treatment after two weeks,and there is statistical significance(P<0.01);Compare the assessment score of the AP group with that of treatment after two weeks,there is no statistical significance(P>0.05);Compare the assessment score of the two groups,there is statistical significance about the difference(P<0.01).(2)Comparision of HAMD assessment scoreAfter t examination,①two weeks after treatment:the APM group decreased in its assessment score compared with pre-treatment,and there is statistical significance(P<0.01);the AP decreased in its assessment score compared with pre-treatment,and there is statistical significance(P<0.01);Compare with the assessment score between the two groups,there is no statistical significance(P>0.05);②four weeks after treatment,the APM group decreased in its assessment score compared with that of treatment after two weeks,and there is statistical significance(P<0.01);Compare the assessment score of the AP group with that of treatment after two weeks,there is no statistical significance(P>0.05);Compare the assessment score of the two groups,there is statistical significance about the difference(P<0.01).(3)Comparision of the score of TCM SyndromeAfter t examination,①Compare within group:After two weeks treatment,the assessment score of the APM group,compared with its pre-treatment,were decreased in areas such as sleeping difficulty,appetite loss,fatigued spirit and lack of strength,occasional deep breaths,irritability,bitter taste and dry feeling,dizzy,headache,chest distress,abdominal distension and the general score,and it has statistical significance(P<0.01);After two weeks treatment,the assessment score of the AP group,compared with its pre-treatment,were decreased in areas such as occasional deep breaths,irritability,bitter taste and dry feeling,headache and the general score,and it has statistical significance(P<0.01);After four weeks treatment,the assessment score of the APM group,compared with its two weeks before,were decreased in areas such as sentimental sadness,sleeping difficulty,appetiteloss,fatigued spirit and lack of strength,lack of interest,occasional deep breaths,irritability,bitter taste and dry feeling,dizzy,headache,chest distress,abdominal distension and the general score,and it has statistical significance(P<0.01);After four weeks treatment,the APM group,compared with its two weeks before,has no significant difference in the score of TCMSyndrome.②Compare between the group:Two weeks and four weeks after thetreatment,the assessment score of the APM group is significantly lower than that of the AP group in areas such as sleeping difficulty,appetite loss,fatigued spirit and lack of strength,dizzy,chest distress,abdominal distension and the general score.The difference has statistical significance(P<0.01).Two weeks after the treatment,comparing with the AP group on aspects such as sentimental sadness,lack of interest,occasional deep breaths,irritability,bitter taste and dry feeling as well as headache,the difference has no statistical significance(P>0.05).However,after 4 weeks treatment,comparing the assessment score with the AP group,the difference has statistical significance(P<0.01).3.Comparision of curative effectEvaluate therapeutic effect by reduction rate of HAMD assessment score.Two weeks after the treatment,the general efficiency of the APM group is 90%and the general efficiency of the AP group is 76.67%and the efficiency difference of the two group has no statistical significance(P>0.05).Four weeks after the treatment,the general efficiency of the APM group is 100%and the general efficiency of the AP group is 80%.The efficiency difference of the two groups has statistical significance(P<0.01).ConclusionBoth APM group and AP group acquire definite clinical effect in treating depressive neurosis of liver-stagnation and spleen-deficiency syndrome,and the former has more advantages in reducing the total score of SDS and the total score of HAMD.In addition,the APM group was superior to AP group in improving the main symptoms score of TCM and reducing the total score of TCM syndrome.It has better clinical efficacy for this syndrome and worth to popularization.