Happy Heart Fang Ning Clinical Efficacy Treating Liver And Spleen Deficiency Observed Cardiac Neurosis

Objective:To observe Xiaoyao ningxin Treating liver and spleen deficiency cardiac neurosis clinical efficacy and safety. Provide new ideas and methods of treatment for the treatment of clinical medicine cardiac neurosis.Methods:The study included select June2013-January2014Wangjing Hospital, China Academy of Traditional Chinese patients with cardiovascular hospitalization or outpatient medical ward. Which test group of30patients in the control group of30patients. Using simple random method, using a random number table to line11,45,46as the start, the provisions of the odd experimental group, even as the control group, according to the order of patient visits, look-up table grouping, were randomly divided into two groups.The control group was orally Oryzanol20mg,3times daily for14days; treatment group Xiaoyao ningxin oral medicine particles (basic side:Chai Hu10g, turmeric10g, Fructus10g, white peony root12g, Magnolia10g, Poria10g, Atractylodes15g, Polygala10g, fried Zaoren30g,2times Albizia30g) addition and subtraction, daily for14days. Recorded before and after treatment TCM syndrome score, Hamilton Anxiety Scale (HAMA) and Hamilton Depression (HAMD) Scale, adverse events, safety indicators, before and after studies of serum alanine aminotransferase (ALT) and creatinine (CRE), urea nitrogen (BUN) and other safety indicators. Results using SPSS18.0statistical software analysis, measurement data using t test, count data using χ2test.Results:1.before treatment for age, sex, disease duration, symptom score, Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale differences (HAMD), ALT, CRE, BUN, CK-MB and other safety indicators not statistically significant (P>0.05), comparable.2.After treatment, the treatment group TCM symptom score was significantly lower than the control group (P<0.05), statistically significant, the treatment group, the total effective rate of89.6%in the control group, the total efficiency of68.3%.3.After treatment, the treatment group Hamilton Anxiety Scale (HAMA) score was significantly lower than the control group (P<0.01), there was a significant difference between the treatment group, the total effective rate of83.0%in the control group, the total efficiency of65.3%in the treatment group was significantly than the control group.4.After the treatment, the treatment group Hamilton Depression Scale (HAMD) score was significantly lower than the control group (P<0.05), total effective rate was79.3%in the control group, the total efficiency of61.8%in the treatment group than the control group.5. Two groups of patients after treatment review ALT, CRE, BUN. Course of treatment in patients with no significant adverse reactions and side effects. Conclusions:1.Xiaoyao ningxin subtraction can effectively reduce the clinical symptoms in patients with cardiac neurosis integration, improve clinical symptoms in patients with cardiac neurosis.2.Xiaoyao Ning Decoction can effectively reduce heart patients with cardiac neurosis Hamilton anxiety scale integration, improve anxiety symptoms in patients with cardiac neurosis.3.Xiaoyao Ning Decoction can effectively reduce heart patients with cardiac neurosis Hamilton depression scale score, improve depressive symptoms in patients with cardiac neurosis.4.Xiaoyao Heart Ning Decoction on cardiac neurosis patient safety indicators had no effect, the security is good.