The Study Of The Relationship Between Tcm Syndrome Types And Quality Of Life In 31 Patients With Advanced Non-small Cell Lung Cancer

Objective:In order to analyze the medication of traditional Chinese medicine and the relationship between the evolution of TCM syndromes in patients with advanced NSCLC and to explore the quality of life in advanced treatment of NSCLC,in order to improve the quality of life of patients with NSCLC,and provide a theoretical basis for the selection and evaluation of curative effect to reduce the family burden and social comprehensive treatment measures.Method:Our cases came from the Department of respiration the First Affiliated Hospital of Anhui TCM University,Department of respiration,cadres and tumor,all the 40 patients met the study inclusion criteria and exclusion criteria in patients with advanced non-small cell lung cancer,lung cancer,TCM syndrome diagnosis standard reference,to collect the patients of different syndrome types and to evaluate the quality of life of patients with lung cancer(Functional Assessment of Cancer Therapy-lung table,FACT-L)Chinese version plus the general situation of the quality of life of patients with information collection,collation,the general condition of patients,TCM syndrome type of traditional Chinese medicine,drug information,survival The quality of each dimension into the database.First,using the Krone Bach coefficient alpha(Chronbach alpha),a scale of credibility,and then select the job,age,sex,marriage,education level,economic status,smoking,smoke powder or contact,pathological types,factors of TCM syndromes and other factors,on the basis of data normality and homogeneity of variance analysis,tested by t test and single factor variance,mean 22 compared with the SNK-q test standard test to P<0.05.A significant difference for P>0.05 is of no statistical significance.The evolution law and the traditional Chinese medicine of TCM Descriptive statistical analysis.Result:1 The study found that the quality of survival in the physiological condition,social /family life,different types of TCM activity dimensions and the total score of quality of life of patients with advanced NSCLC have significant difference(P<0.01),syndrome of qi stagnation and blood stasis,Qi deficiency and phlegm dampness were the lowest,the difference was statistically significant(P=0.002);the physiological condition dimension,patients with syndrome of qi stagnation and blood stasis,Qi and Yin deficiency of patients with the lowest,the difference was statistically significant(P=0.005);social / family life dimension,syndrome of qi stagnation and blood stasis of the most high,Qi deficiency and phlegm dampness were the lowest,The difference was statistically significant(P=0.043);emotional status,patients with syndrome of qi stagnation and blood stasis Qi deficiency and phlegm dampness were the lowest,the difference was statistically significant(P=0.005);activity,the highest type of phlegm heat in the lung,Qi deficiency and phlegm dampness type is low,the difference was statistically significant(P=0.047);other factors,there is no significant differences in the syndrome score(P=0.146).2 The study found that in the dimension of the quality of physiological condition of survival,gender and economic conditions of yin deficiency and toxic heat type,economic level have significant difference on effects of syndrome of qi stagnation and blood stasis(P<0.05);social/family life dimension,the economic situation has significant difference on syndrome of qi stagnation and blood stasis(P<0.05);emotional status dimension on gender,type and phlegm heat in the lung yin deficiency and toxic heat,yin deficiency and toxic effects of marriage on heat type had significant difference(P<0.05);the activities of dimension,influence of occupation on the deficiency of Qi and Yin with significant difference(P<0.05);other factors of gender,position Industry of syndrome of qi stagnation and blood stasis,phlegm heat in the lung on the economic level,influence the pathological type of Qi Yin deficiency had significant difference(P<0.05).3 For the 4 follow-up of 31 cases of patients with advanced,a total of 124 times,with Yin deficiency and toxic type majority,a total of 31 cases(25%),Qi deficiency and phlegm dampness type in 27 cases(22%);TCM syndrome type distribution for the first time in the investigation period,syndrome of qi stagnation and blood stasis,accounting for52%;second times with phlegm heat lung type and yin deficiency heat toxin type,accounted for 35%,29%;third Yin toxic type of deficiency of both qi and Yin type,accounted for 39% and 29%;the last time to Qi Yin deficiency phlegm dampness type and Qi deficiency mainly accounted for 42% and 32%.4 Advanced drug application frequency in patients with NSCLC were higher in licorice,astragalus,Poria,Atractylodes,Fritillaria thunbergii,Scutellaria barbata.Conclusion:1 Different syndromes in patients with advanced NSCLC in the dimension of the quality of physiological condition of survival,social / family life dimension,differences in activity dimensions and total score of quality of life.According to the different clinical syndromes on the quality of life of a dimension for targeted treatment,in order to improve the quality of life of patients.2 Gender,occupation,marriage and economic level have different effects on the quality of life of the patients with different syndromes of advanced NSCLC.3 NSCLC TCM syndrome with Yin deficiency type more heat,Qi deficiency and phlegm dampness,and the extension of time with patients,Qi and Yin deficiency proportion is increasing.4 Traditional Chinese medicine for tonifying the spleen is widely used in patients with advanced NSCLC.