Shenlingbaizhu Decoction In Treating Diarrhea Type Irritable Bowel Syndrome Of Systematic Evaluation And Clinical Observation

Objective: system evaluation of Shenlingbaizhu powder in the treatment of diarrhea predominant irritable bowel syndrome is safe and effective and observe the effect of Shenling Baizhu powder in the treatment of diarrhea type irritable bowel syndrome clinical efficacy.Methods:1. System evaluation: the use of system evaluation method, retrieval of Shenling Baizhu powder in the treatment of diarrhea predominant irritable bowel syndrome: a randomized controlled trial, screening of qualified, quality evaluation, international application based collaborative network of medical certificate provided statistical software Revman5.3 statistical data and the Jadad score of quality evaluation. According to the clinical test measures in different subgroups of the collected data were analyzed and the heterogeneity test Meta-. The 2 part of clinical research: choose the subjects a total of 60 patients were randomly divided into experimental group and control group, 30 cases in the experimental group, 30 cases in the control group. The experimental group was given Shenlingbaizhu San Decoction; the control group was given pinaverium bromide tablets and Peifeikang capsule for 4 weeks. Clinical effect after one course of treatment.Results: 1. System evaluation: after screening, and ultimately into the 18 studies, 1446 cases, according to the different test measures for two groups. The results showed that the Shenlingbaizhu powder in the treatment of D-IBS clinical total effective rate, clinical symptoms total score, abdominal pain, diarrhea curative effects were superior to the control group, were statistically significant and clinically meaningful and no serious no response. The above results show that shenlingbaizhusan Decoction for the treatment of D-IBS is safe and reliable, provide reference for clinical medication. 2. The clinical research part: the comprehensive clinical curative effect, the experimental group the total efficiency was 96.7%, the control group, the total effective rate was 86.7%, the experimental group, the total efficiency is higher than that ofthe control group. After analysis, two groups exist significant difference(P < 0.05) in clinical comprehensive therapeutic effect improvement of the experimental group than the controls. The test group and control group, symptom score had significant difference(P < 0.05), indicating improvement in the total score of TCM syndrome, the experimental group than the control group.Conclusion: 1. The evaluation system analysis of additive Shenlingbaizhu decoction can improve the D-IBS clinical curative effect, but due to the evaluation of the system into the study of low quality and small sample size, drug safety is not clear, still need high quality randomized controlled trials were further evaluated. 2 clinical studies showed that Shenlingbaizhu decoction treatment of diarrhea type irritable bowel syndrome is better than pinaverium bromide tablets and Peifeikang capsule.