Objective: With the development of clinical diagnosis and treatment technology, the treatment have a profound impact to the cervical cancer patient’s life, although there is a long-term survival of patients with cervical cancer. In recent years, the prevalence of cervical cancer is increasingly younger. For young patients, the treatment of cervical cancer has not only impact on the body, but also has influence on the psychological, social and family aspects.Therefore, the medical workers should pay much more attention to the problems of life quality after treatment of cervical cancer in younger women. The objective of this investigation is to evaluate the quality of life and sexual function of young cervical cancer patients after treatment in our hospital; and to investigate the factors which affect the quality of life and sexual function. Then to provide a theoretical basis for clinical decision-making and the application of clinical nursing intervention measures in the future.Methods:The patients were followed by letters and telephone interviews. The social demographic questionnaire, the Functional Assessment of Cancer Therapy(FACT-G) and Female Sexual Function Index scale(FSFI) were used to investigate 97 cervical cancer patients under the age of 35, who were treated in our hospital between January 2011 and December 2014. The results were analyzed by SPSS13.0 software statistically.Results:1 97 younger cervical cancer patients were involved in the study eventually.2 The quality of life:1) Quality of life score: The total score of FACT-G was 81.14±12.79. Each dimension score: The average score of physical well-being: 23.43±3.77; The average score of social/family well-being: 21.24±4.84; The average score of emotional well-being: 18.63±3.74;The average score of functional well-being: 20.86±4.29.2) The single factor analysis to life qualitya. Age and fertility status: There was no significant difference about life quality and each dimension score among different age and fertility status(P> 0.05).b. The degree of education and the source of medical costs: The life quality and each dimension score were lower in the patients without medical insurance or with low degree of education, except social/family well-being.c. The residence:The life quality score in rural patients was lower than in the urban patients(P< 0.05). The differences among social/family well-being and functional well-being were significant(P< 0.05).d. The family income:The life quality score and each dimension score were lower in low income family(P< 0.05).e. Radiotherapy :The radiotherapy after operation had a significant influence on life quality and each dimension score(P< 0.05). The life quality score was lower in patients getting radiotherapy after operation, than in patients without radiotherapy.f. The chemotherapy and stage: The life quality and each dimension score were lower in patients getting chemotherapy and late clinical stage, except social/family well-being(P< 0.05).g. The number of complication: There was significant difference between different numbers of complication, about the life quality, physical well-being, emotional well-being(P< 0.05).h. Sexual dysfunction:The life quality score and each dimension score were low in patients with sexual dysfunction(P< 0.05).3)The multiple- factor analysis to life qualityAccording to multiple stepwise regression analysis, life quality of younger cervical cancer patients was influenced by sexual dysfunction, medical insurance, family income, clinical stage, and the education degree(P< 0.05). Especially, the life quality of younger patients were influenced by sexual dysfunction much more.3 Sexual functionIn the investigation, the FSFI total score and each dimension score in 97 cervical cancer patients: Sexual desire dimension score 2.80(1.2-5.4),Sexual arousal dimension score 3.28(0-6.0),Vaginal lubrication dimension score 3.64(0-6.0),Orgasm dimension score 3.77(0-6.0),Sexual satisfaction dimension score 4.06(0.8-6.0),Sexual pain dimension score 4.02(0-6.0),total score 21.61(2-33.0).Total score 26.55 was seen as decision point of sexual dysfunction according to FSFI standard. The patients below score 26.55 were looked as sexual dysfunction. Then 67.0% patients had sexual problems.2) The single factor analysis to sexual functiona. The degree of education: There was significant difference between different degree of education according to total FSFI score、sexual arouse、orgasm、sexual satisfaction and sexual pain(P<0.05)。b. The medical cost source: Total FSFI score was higher in patients with medical insurance than in self- paying patients, especially on orgasm、sexual satisfaction and sexual pain(P<0.05).c. The family income: Total FSFI score and each dimension score was lower in patients with low income, except vaginal lubrication dimension(P<0.05).d. The residence: Total FSFI score and each dimension score in rural patients were lower than that in urban patients, except sexual desire and sexual pain(P<0.05).e. The clinical stage: Total FSFI score and each dimension score were different in different stages(P<0.05).f. The adjuvant therapy:The total FSFI score and each dimension score were higher in patients without radiotherapy than in patients getting therapy(P<0.05). There was no difference between patients getting chemotherapy or not.g. The numbers of complication: The total FSFI score and each dimension score was lower in patients with complications ≥3(P<0.05).2)The multiple- factor analysis to sexual functionAccording to multiple stepwise regression analysis, sexual function was influenced by radiotherapy, clinical stage(P< 0.05), especially radiotherapy.Conclusions:1 The life quality is low in younger patients after therapy. The late stage, low family income, no medical insurance, low degree of education and low sexual function reduce the life quality level. The life quality of younger cervical cancer patients is influenced by sexual dysfunction greatly.2 The level of sexual function was low in younger patients. The late clinical stage and radiotherapy after operation damaged sexual function. |