| ObjectiveThe objective of this research is to estimate the therapeutic effect of the treatment for acne of phlegm coagulation-blood stasis constitution by moxibustion with back blood-letting, to provide a distinctive treatment with simplified operation and reliable effect for the patients with acne.MethodsBased on the inclusion criteria,66 cases of acne of phlegm coagulation-blood stasis constitution were selected and randomly divided into the treatment group(moxibustion with back blood-letting therapy)and the control group (only back blood-letting), with 33 cases in each group. Patients in both groups were given primary treatment in local skin lesions. The treatment group received box-moxibustion combined with back blood-letting. Box-moxibustion was used on the abdomem, covering the acupoints of shenque, zhongwan, xiawan, qihai and guanyuan. Back blood-letting was given on one of the two acupoint groups alternately each time, one of which is feishu, geshu, weishu while the other is jiaji in T3/7/12. The control group were treated only by back blood-letting, the operation method of which is the same as the treatment group. Treatments of both groups were required in every three days to ensure two treatments per week. Four weeks were a course, and the treatment courses lasted 8 weeks. Record the scores of skin lesions and disease grades before treatment and after each course. Analyze all data by statistical methods and compare the total efficiency between the two groups.ResultsThere were 66 patients involved with 2 shedding cases in the control group. The factual cases included 33 patients in the treatment group.while those in the control group were 31.1. Basic information comparison(1)Age comparison:The age of the treatment group was 24.30±4.305, while that of the control group was 24.13±4.326. By t test, t was 0.161, P was 0.161, which showed there was no significant difference (P>0.05) and the two groups were comparable.(2)Disease course comparison:The course of the treatment group was 15.88±21.210, while that of the control group was 14.97±16.123. By t test, t was 0.193, P was 0.848, which showed there was no significant difference (P> 0.05) and the two groups were comparable.(3)Gender comparison:There were 9 males and 24 females in the treatment group, while there were 4 males and 27 females in the control group. By Chi-square,χ2 was 2.039, P was 0.132>0.05, which showed there was no significant difference and the two groups were comparable.2. Observation indexes comparison:(1)Skin lesion scores:By t test:①Comparing between the two groups before treatment, t was 1.162, P was 0.250> 0.05, with no significant difference. ②After 4 weeks, for the treatment group comparing with the scores before treatment, t was 24.112, P was 0.000< 0.01; and for the control group, t was 19.219, P was 0.000< 0.01, which were both showing significant difference. Comparing between the two groups, t was-0.475, P was 0.636> 0.05,with no significant difference. ③After 8 weeks, for the treatment group comparing with the scores after 4 weeks treatment, t was 19.428, P was 0.000< 0.01;and for the control group, t was 15.005, P was 0.000< 0.01, which were both showing significant difference. Com-paring between the two groups, t was-2.455, P was 0.017< 0.05, with significant difference.(2)Skin lesion score difference:By t test:①After 4 weeks, comparing between the two groups, t was 3.385, P was 0.001< 0.01, showing statistically significant difference.②After 8 weeks, comparing between the two groups, t was 4.261, P was 0.000< 0.01, showing statistically significant difference.(3)Disease grades:By rank-sum test:①Comparing between the two groups before treatment, Z was-0.577, P was 0.564> 0.05, with no significant difference.②After 4 weeks, for the treatment group comparing with the grades before treatment, Z was-6.285, P was 0.000< 0.01;and for the control group, Z was-6.592, P was 0.000< 0.01, which were both showing significant difference. Comparing between the two groups, Z was-0.216, P was 0.829> 0.05, with no significant difference. ③After 8 weeks, for the treatment group comparing with the grades after 4 weeks treatment, Z was-4.638, P was 0.000< 0.01;and for the control group, Z was-3.376, P was 0.001< 0.01, which were both showing significant difference. Com-paring between the two groups, Z was-2.275, P was 0.023< 0.05, with significant difference.3. Curative effect comparison:After 4 weeks of therapy, among 33 cases of the treatment group,0 case was clinically cured,2 cases had markedly effect,19 cases were improved and 12 cases were invalid, which contributed a curative rate as high as 57.64%. Among 31 cases of the control group,0 case was clinically cured or had markedly effect,16 cases were improved and 15 cases were invalid, which contributed a curative rate as high as 51.61%. By rank-sum test, Z was-1.193, P was 0.233>0.05, with no significant difference.After 8 weeks of therapy, among 33 cases of the treatment group,2 case were clinically cured,24 cases had markedly effect,5 cases were improved and 2 cases were invalid, which contributed a curative rate as high as 93.94%. Among 31 cases of the control group,0 case was clinically cured,14 cases had markedly effect,13 cases were improved and 4 cases were invalid, which contributed a curative rate as high as 87.10%. By rank-sum test, Z was-2.806, P was 0.005<0.01, with statistically significant difference.ConclusionBoth the treatment and control group acquire definite clinical effect in treating acne of phlegm coagulation-blood stasis constitution, and and the former is better than the latter in reducing disease grades and improving skin lesions and therapeutic efficacy. |
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