Analysis On The Rules Of Prescriptions Of Professor Xu Youjia For Treating Chronic Cough In Children By Data Mining Method

ObjectiveTo analy professor Xu’s experience and sum up the regularity of prescription in treating chronic cough in children based on the traditional Chinese medicine inheritance support system(TCMISS).In order to confirm the adaptability of the academic idea that children’s constitution is deficiency-cold in treating chronic cough in children. And for the result, we expected, can provide a new therapeutic method for clinicians.MethodsThe research collects 129 prescriptions in 46 medical records of outpatient with chronic cough in children that Professor Youjia Xu remedied in the past three years. And then we do some data statistics and analysis based on the TCMISS to carry out a discussion of the prescription rule. At last we used the results to prove the TCM syndrometype. And combining with the summary after training followed by preferred Xu.And then conclude professor Xu’s experience and sum up the regularity of prescription in treating chronic cough in children.ResultsT75 kinds of herbs are foud by analyzing 129 prescriptions.And the top 17 most frequent herbs are Radix Glycyrrhizae, Pericarpium Citri Reticulatae, Rhizome Pinellnae Praeparata, Radix Sileris, Fired Fructus Oryzae Germin, Polygala Tenuifolia, Fructus Xanthii, Acorus Tatarinowii, Mango Seed,Areca-nut, Schisandra Chinensis, Radix Stemonae, Poria Cocos, Chicken’s Gizzard-menbrane, Semen Raphani, Magnolia Flower, Bighead Atractylodes Rhizome. There are 62 kinds of combinations including 9 categoies of herbs that are found in the study. Most of the herbs which with meridian tropism in lung, spleen and stomach are warming, calm, pungent, bitter and sweet. And most of the classification of the herbs are digestant herb, wind-cold-effusing medicincal, herb for restoring vital energy, expectorant cough suppressant and anti-asthmatic herb and qi-regulating herb.With the support of system,14 core combinations and 7 new prescriptions are found. And the 7 new prescriptions are Fructus Schizandrae, Peach Seed, Bupleurum, Poria Cocos, Fructus Xanthii;Folium Microcotis, Cortex Mori Radicis, Saposhnicovia Divaricata, Radix Peucedani; Rhizoma Belamcandae, Cortex Mori Radicis, Pericarpium Citri Reticulatae, Malt, Perilla Leaf;Salviae Miltiorrhizae, Poria Cocos, Semen Arecae, Semen Arecae, Peach Seed, Radix Angelicae; Fired Fructus Oryzae Germin, Poria Cocos,Semen Arecae, Semen Arecae, Peach Seed, Radix Angelicae;Acorus Tatarinowii, Mango Seed, Semen Raphani, Radix Stemonae, Chicken’s Gizzard-menbrane, Dried Ginger; Atractylodes Macrocephala Koidz, Calyx Kaki, Polygala AmfIra, Jujube, Poria Cocos, Fructus Xanthii.ConclusionProfessor Youjia Xu treats chronic cough in children by using his theory of "children’s constitution is deficiency-cold".And he treats chronic cough from lung, spleen and stomach and in especial pays attention to tonify spleen. And He commonly uses warming or calm herbs. On the basis of the study result, we know that phlegm wet cough is the most common type of syndrome.