The Multiple Regression Analysis To The Post Stroke Depression’s Relative Factors

Object:To evaluate the related factors of post-stroke depression were retrospectively analyzed, to definite the relationship between various factors to clear after stroke occurrence and lesion location, depression and social support and the patient’s own factors, so as to prevent the development of post-stroke depression, improve the quality of life, promote the stroke patients offer epidemiology evidence for the functional recovery of patients etc..Methods:1 Clinical data:388Patients all come from the integration of traditional Chinese and West medicine ward and out-patient clinic of Affiliated Hospital of Hebei University, and some community patients from October, 2012 to October, 2014. 320 patients of 388 patients conform to medicine diagnostic criteria. All of the patients included in the standard will beinvestigate for general information(such as gender, age, culture level, etc.) and professional medical(such as image information, course length, stroke frequency, etc.),after signing of the informed consent. When the patients in stable condition after(2 weeks),we use The US National Institutes of Health Neural Function Defect Stroke Scale and Hamilton Depression Scale to assessment physical structure and function injury, daily life movement function and severity of depression and so on. Stroke diagnosis standards are according to the Fourth National Conference on cerebrovascular diseases diagnostic criteria. And all patients confirmed by skull CT or MRI, head MRA 、head and neck,CTA or DSA to understand the intracranial and extracranial blood vessel. We use Hamilton depression rating scale as the evaluation criteria of depression. The total score < 8 divided into depression, 8-17(excluding17) were divided into mild depression, 17-24(excluding 24) divided into moderate depression, more than 24 divided into severe depression. We use single factor analysis and multiple stepwise regression analysis to analyze the relevant factors on depressive symptoms.2 The group process:According to the order of treatment in patients with 388 Cases, including 22 patients with severe aphasia or aggravation of clinical death induced bydisturbance of consciousness; discharge diagnosis of peripheral neuropathy, posterior circulation ischemia or other in 9 cases;16 cases of hospitalization according to laboratory report and related auxiliary examination that has serious heart liver and kidney diseases; in 15 cases,for infarction of special patients induced by hallucinations or psychiatric symptoms; signing the informed consent(Annex5), but declined to 6 subjects. Finally in 320 cases, including 185 cases of male, female 135 cases, the final into the group of cases is the general situation, history, imaging data, social support scale, Hamilton depression scale, USA NIH stroke scale investigation. The result of the investigation after the initial order, each related assignment is found in Annex1, 2, 3, 4.3 Research methods: By using the method of questionnaire to all patients who meet the inclusion criteria of questionnaire. The contents of the questionnaire include three aspects: the basic situation of the investigation of patients with clinical information, investigation and survey of three aspects: the general information including age, body mass index, education level, occupation and other types of medical information; including stroke lesion location, quality, duration of apoplexy; questionnaire including social support rating scale Hamilton depression scale, the National Institutes of health, America score of neural function defect scale. In the process of investigation to fill in the questionnaire were surveyed and unified guidance language recovery site, in order to reduce the initial error of measured data, provided by two medical personnel to avoid fixed tips, guide language, according to the comprehensive performance score of patients.Data were collected and analyzed statistically for professional summary.Results:1 This study collected 388 Cases, the final completion of the survey in 320 cases, including 185 cases of male, female 135 cases, for various reasons, fall 68 cases, less than the total number of 20% cases observed.2 in the observation of 320 cases of patients, the incidence of post-stroke depression in 146 cases, the total incidence rate was45.63%, 91 cases of mild depression(62.33%), 42 patients with moderate depression(28.77%), 13 severe cases(8.9%).3 All studies factors included sex, age, smoking history, drinking history, family income, culture degree, occupation type, body mass index, population, social support score stroke position, nature of stroke, risk factors, disease duration, number of nerve function defect degree, stroke number. By single factor analysis, sex, culture degree, the degree of social support, the nature of stroke, the number of risk factors, neural function defect degree of the 6 factors with statistical significance. The 6 risk factors into the multiple stepwise regression equation, sex, culture degree, the degree of social support, risk factors with statistical significance number, the degree of neurological deficits, stroke nature because of 95% confidence interval is too wide and not of clinical significance.Conclusion:Treating post-stroke depression is not a single factor, the factors related to various. The study found that, more common in men than in women with post-stroke depression, are positively related with culture degree, the number of risk factors, neural functional defect and post stroke depression(risk factors), and the degree of social support and depression after stroke showed a negative correlation(protective factors). Not found the age, smoking history, drinking history, family income, occupation type, body mass index, stroke position, course of disease, stroke frequency to PSD had significant correlation. Although the stroke properties into the equation, but because the confidence interval width too large,so this need for further large-scale clinical case studies to confirm.