Clinical Observation Of Anti-allergic Cough Remedy Granules In The Treatment Of CVA And Effects Of FeNO

Objective: In this article, by comparing the anti-allergic cough remedy particles, pure western medicine and anti-allergic cough remedy particles combined western medicine treatment of cough variant asthma three methods(cough variant asthma, CVA) of clinical research, observe the three before and after treatment, clinical symptoms, signs, cough symptom integral and fractional exhaled nitric oxide( Fe NO) such as numerical indicators, to evaluate the clinical curative effect of treatment of CVA a anti-allergic cough remedy particles, and discuss the influence degree of the three methods for inflammatory indexes Fe NO differences, especially the influence of traditional Chinese medicine for its.Methods: We will accord with standard of cough variant asthma medicine diagnosis and syndrome differentiation of traditional Chinese medicine belong to the wind made 90 patients of pulmonary syndrome according to the design method of randomized, controlled trials are divided into three groups: 30 cases in group A(given Chinese medicine anti-allergic check rinse granule treatment); B group and control group(30 cases given budesonide powder inhaler standard western medicine treatment); C group and control group(30 cases for traditional Chinese medicine anti-allergic check rinse particles joint budesonide powder inhaler standard western medicine treatment), the treatment course 12 weeks. Of signs and symptoms of three groups of patients, general index, safety index and cough symptoms integral and Fe NO numerical indicators before and after treatment respectively test records, and SPSS20.0 statistical software is adopted to improve the contrast.Results: 1.The clinical curative effect of standard: after 12 weeks of treatment, the three groups of overall curative effect comparison, A group total effective rate 86.7%, B group total effective rate 83.3%, total effective rate of group C 96.7%. 2.Cough symptoms integral contrast: three groups of patients before treatment cough symptoms integral by the statistical analysis of no significant difference(P > 0.05); After 12 weeks of integral has dropped significantly, down was statistically significant(P < 0.05). In terms of integral improvement after statistics analysis, no obvious difference was found between group A and group B, no statistical significance(P > 0.05), but is better than that of group A and group C was statistically significant(P < 0.05), and also is better than that of group B, group C was statistically significant(P < 0.05). 3. Fe NO level changes: three groups of patients before treatment breath nitric oxide levels after statistics analysis, no significant difference(P > 0.05); Values have declined significantly after 12 weeks, taking down was statistically significant(P < 0.05). In A degree of decline after statistics analysis, no obvious difference was found between group A and group B(P > 0.05), but the degree of decline in group C than in group A, was statistically significant(P < 0.05) than in group B, with statistical significance(P < 0.05). 4.general index and safety index: three groups of patients before treatment and after 12 weeks, in terms of general index and safety index test, through analysis, there was no significant difference between group and group(P > 0.05). Suggest three groups of comparable, three groups during treatment had no adverse events occurred, no coming off.Conclusion: 1 Anti-allergic cough remedy particles with breeze xuan lung, spasmolysis cough, cough variant asthma type wind evil committed lung curative effect is remarkable. 2 Anti-allergic cough remedy particles can lighten the patients symptoms and signs, reduce patient cough symptoms integral, improve curative effect 3 Anti-allergic cough remedy particles can reduce Fe NO level.