Peach Siwu Decoction On The Primary Curative Effect Observation Of Blood Stasis Type Of KOA

Objective:By observing the peach siwu for primary treatment of blood stasis type of KOA, provides new thinking for clinical treatment of the knee arthritis; According to the strict classification of blood stasis type of traditional Chinese medicine (TCM) treatment in patients with osteoarthritis effect, and then reverse KOA this parting of the right or not, for knee arthritis overall classification provides the basis for a reverse, thus promote the classification research of KOA.Methods:Collection-in October 2014, December 2013 in henan province, luoyang bonesetting hospital outpatient clinic bone and conform to the conditions in the primary blood stasis type of knee osteoarthritis patients, a total of 80 cases. All included in the patients were informed consent signed drug clinical trials. In patients with random number table can be divided into two groups, experimental group taking peach siwu decoction; Take glucosamine hydrochloride in the control group, treatment cycle for 6 weeks, all of the patients before treatment and treatment 2 weeks, 4 weeks, 6 weeks, 3 months after the drug was stopped, detect and record the pain visual analog scale (VAS) score, blood stasis type of KOA TCM symptom integral, knee joint WOMAC index, serum IL-1 beta, TNF alpha content, application of statistical software for statistical analysis of all data observed in the two groups in different monitoring point of observation indexes of difference.Results:Experimental group compared with control group cases balance in age, gender, course and grade of X line and into the group before 1 day VAS score, the traditional Chinese medicine clinical symptom score, the WOMAC index,IL-1 beta, TNF alpha numeric and no significant difference (p> 0.05), two groups of cases more comparable. Two groups of 2,4,6 weeks after treatment than before treatment,1 day, VAS score, the traditional Chinese medicine clinical symptom score, the WOMAC index beta, TNF-alpha, IL-1 beta value, are improved to varying degrees:2,4 weeks after treatment between the two groups, the WOMAC index, IL-1 beta, there was no significant difference between the TNF alpha, but VAS score, the traditional Chinese medicine clinical symptom score improvement experimental group is better than that of control group (p<0.05).6 weeks after treatment between the two groups, VAS score, the traditional Chinese medicine clinical symptom score. WOMAC index, IL-1 beta, TNF alpha value to improve the situation had no significant difference. Six weeks after the patient’s overall treatment effect between the two groups, no significant difference, stopped for 3 months visit when two groups of patients of VAS score. TCM clinical syndrome score no difference, but the knee joint WOMAC index, IL-1 beta, TNF alpha numerical difference is statistically significant, the control group is better than that of the experimental group.Conclusion:(1) with the pink KOA siwu decoction for primary blood stasis syndrome in the short term can be use as the efficacy of glucosamine hydrochloride capsules, and peach siwu decoction of traditional Chinese medicine to relieve knee pain and improve knee arthritis symptoms is working faster than glucosamine hydrochloride group, knee joint glucosamine hydrochloride group control and reduce inflammatory factor, to improve the function of knee joint, long-term efficacy is better than pink siwu decoction group.(2) pink siwu soup attending blood deficiency and blood stasis, is a classic formula of a cultivated and invigorate the circulation of blood, the results confirmed that the primary blood stasis type of knee osteoarthritis treatment effect is exact, can reverse inference from bleeding and blood stasis type of knee osteoarthritis is common in clinical, and this kind of classification is based on.