Polysomnographic Clinical Study Of Generalized Anxiety Related Insomnia Deficiency Or Excess Between

Objective:By using Cross sectional data acquisition to collect Chinese medical information and Hamilton anxiety scale, Pittsburgh sleep quality index rating scale evaluating Insomnia related with generalized anxiety disorder. Observing the difference between pathogenic fire derived from stagnation of liver group of insufficiency of heart and spleen in the area of TCM syndrome elements, insomnia and anxiety degree. Each member in the study will be tested by Polysomnography,aim at observing whether there are different in PSG sleep structure,cha-racteristics and differences of the sleep process. Then give basis for the study of mental disea-se such as generalized anxiety disorder by further using polysomnographic parameters in TC-M syndrome type in all aspects, summarizing, and applied to clinical diagnosis and treatment of TCM in differences.Methods:Collection in January2013to December2013visits in the third affiliated hospital encephalopathy Division outpatient and ward service of Traditional Chinese Medicine. All80standard subjects will be having TCM syndrome differentiation by2deputy chief physicians, then being examine and verified by an experienced physician. Conforms to the diagnostic criteria of insomnia related with generalized anxiety disorder, divided into group of pathogenic fire derived from stagnation of liver group of insufficiency of heart and spleen27, the group of insufficiency of heart and spleen28and normal group25people.And using the Polysomnography system after being grouped by syndrome differentiation of traditional Chinese Medicineyndrome differentiation. Each patient in the study accepts an8hours long Sleep monitoring from10pm to6am under the condition of no hypnotics. The data will be recoded and all data through Statistical frequency analysis and chi square test method.Results:The results show that the common symptoms of Traditional Chinese Medicine(TCM)of55patients who are being diagnosed with Generalized anxiety related insomnia are those symptoms as irritability difficulty falling asleep, palpitations, dizziness, timid, dream, wakeup early, tinnitus, forgetfulness. The first5common symptoms of traditional Chinese Medicine in group of pathogenic fire derived from stagnation of liver are Irritability, Chest rib Pain,difficulty falling asleep, fear and dream, The first5common symptoms of traditional Chinese Medicine in group of insufficiency of heart and spleen are Palpitation, timid, difficulty sleeping, dizziness and fatigue.pathogenic fire derived from stagnation of liver had sleep latency extended compared with the group of insufficiency of heart and spleen and there were statistical significance (P<0.05). Compared with normal group, group of pathogenic fire derived from stagnation of liver and group of insufficiency of heart and spleen have less WSW and there were statistical significance (P<0.05); Group of insufficiency of heart and spleen decreasing more then group of pathogenic fire derived from stagnation of liver. Compared with normal group, groups of pathogenic fire derived from stagnation of liver and insufficiency of heart and spleen have increasing in the number of awakening while decreasing in sleep efficiency and there were statistical significance (P <0.05); But for the Sleep maintenance index group of pathogenic fire derived from stagnation of liver compared with the group of insufficiency of heart and spleen had no statistical significance (P>0.05).Conclusion:1. Compared with normal group, group of pathogenic fire derived from stagnation of liver and group of insufficiency of heart and spleen have less sleep duration, less sleep latency extending, less SWS, less REM period but with a increasing in the number of awakening. Displaying decreased sleep efficiency2. Group of pathogenic fire derived from stagnation of liver have longer sleep latency than group of insufficiency of heart and spleen, group of insufficiency of heart and spleen decreased obviously compared with the group of pathogenic fire derived from stagnation of liver in SWS.