| Depression is one of the diabetes complications that seriously threat diabetes patients body and mind.Patients with diabetes in31.4%of patients with depression,including severe depression accounted for14.3%, and80%of the patients relapse,the suicide rates as high as10%in addition.In recent years,the world health organization returned Type2diabetes to non-communicable chronic disease related to the way of life,and emphasized the importance of psychological stress played in the process of diabetes occurred.Obviously, diabetes harm the patients in the body as well as the psychological,and merger depression impose heavy psychology burden to the patients.Studies show that blood glucose of patients with diabetes associated with depression is not easy to get a satisfactory control, microvascular and vascular and other risk of complications may be higher than ordinary people with diabetes. There is evidence to show that depression, anxiety and other negative emotions may increase diabetes illness, antidepressant treatment can improve diabetes patients with depression of the state of depression, but some antidepressant drugs adverse to control blood glucose.This study aims to the development of traditional Chinese medicine has little side effects which can prevent and cure function and depression of diabetes, to improve patients with diabetes mellitus metabolic abnormalities and depressive symptoms, help the patients to get rid of negative psychology and improve the quality of their life, which is of far-reaching significance.This study use the research method of prospective and contrasted,refering to the world health organization experts suggest the consulting report of Type2diabetes diagnosis and classification standards in1999,Zung’s depression rating scale and HAMD depression scale.The patients accord with the liver-stomach disharmony and heart yin losses of the Chinese medicine diagnosis and classification.Through the application of Xiaochaihu soup, Suanzaoren soup and Huangjing Dan to add and subtract, following the law of Lift depression, calm the nerves and tonifying qi and yin to cure57patients (27cases in treatment group and control group in30cases) with diabetes mellitus and depression.Through the Chinese herbal medicine new medicine clinical guiding principle of curative standard which the health ministry promulgated in March1993to effect assessment on symptoms to observe the curative effect of the patients with diabetes mellitus and depression. The results show thatusing Xiaochaihu soup, Suanzaoren soup and Huangjing Dan to add and subtract in the treatment of diabetes patients with depression can obviously improve the diabetes patients with clinical symptoms of depressions with liver-stomach disharmony and heart yin losses syndrome.Compared with controls, the influence of the treatment group to fasting blood glucose, glycated hemoglobin, four lipid profile statistical no significant differences. Safety assessment, the treatment group in liver function (cereal third transaminase, aspertate aminotransferase), kidney (creatinine) after treatment and therapy is statistics before no significant differences. In urea nitrogen treatment group therapy fell in more before treatment. This study shows that using Xiaochaihu soup, Suanzaoren soup and Huangjing Dan to add and subtract in the treatment of diabetes depression state is safe and effective. |