Huo Li Su Oral Liquid Unite Tandospirong Citrate Capsule Treatment Of Epilepsy With State Of Anxiety And Clinical Observation

Objective: Epilepsy is a chronic disease of Neurology, a recurrentcommon in the literature reported epilepsy associated with anxiety theincidence of epilepsy patients is about20%-55%.With the modern medicalmodel conversion to bio-social-psychological model of epilepsy associatedwith psychological problems, especially anxiety disorders has been moreemphasis on control seizures while reducing anxiety attack, how to improveepilepsy patients quality of life has become a must social development.Cramer et al study found that if appropriate treatments for epilepsy patients tothe hospital for psychological problems are not given, the more the number ofvisits to the hospital, the higher the medical expenses spent to control epilepsy,the longer disease duration. Therefore, in the comprehensive treatment ofepilepsy patients, timely and appropriate treatment of psychological problemsis a very important part in the clinical treatment of epilepsy. Research: Withthe continuous development of society, more and more clinicians from asimple control epileptic seizures into more concerned about the patient’smental status, epidemiological survey found, stroke, Parkinson’s, epilepsyassociated with anxiety prevalence rate is higher than the normal population,respectively,19.5%,21.9%,24.1%, of which epilepsy is associated with thehighest prevalence of disorders of psychological conditions. Home and abroadfor the psychological condition of epilepsy research recently received moreand more attention, but relatively little research in this area have been found, Istudy the huo li su oral liquid unite tandospirong citrate capsule treatment ofepilepsy with state of anxiety and clinical observation.Methods:162cases of epilepsy patients with anxiety state (Syndrome differentiation of traditional Chinese medicine gan shen qi xue kuixu). Wererandomly divided into a control group (30cases) and treatment group (32cases), according to the random number table control group at the same timeto give the basic treatment of the antiepileptic (oxcarbazepine) Citrusmedical rafters acid tandospirong citrate capsule treatment, the treatmentgroup huo li su oral liquid unite tandospirong citrate capsule treatment givenantiepileptic basic treatment (oxcarbazepine), grouping the two groups ofpatients Scale score before The difference was not statistically significant.2The therapeutic efficacy:○1control group and the treatment groupwere in treatment baseline,4weeks,8weeks to give the Hamilton AnxietyScale (HAMA) score, determination of the validity of HAMA reduction rateof change, the cure for Less fraction≥80%, markedly reducing rate≥50%-<80%, improved for the reduction rate of≥30%-<50%, the invalid for Lessfraction <30%;○2blood5-HT receptor reduce The degree of change. Thisstudy uses the Hebei Medical Experimental Center blood5-HT receptornormal standard: Female80-450ng/ml, Male40-400ng/ml.Results:1Treatment group after4weeks of treatment,8weeks HAMA reductionrate and blood5-HT receptor score difference was statistically significant (P<0.05). Patients with anxiety, restlessness, irritability, mood than beforetreatment improved markedly, good seizure control, independent living,quality of life improved significantly.2Control group in treatment after4weeks HAMA reduction rate andblood5-HT receptor score difference was not statistically significant (P>0.05),the difference was statistically significant (P <0.05) rating in8weeks, patientswith anxiety gradually improved, but the slow onset compared with thetreatment group.3Control group and the treatment group8weeks of treatment than beforetreatment of HAMA reduction rate and blood5-HT receptor score significantdifference (P <0.01), the method of clinical effects of the treatment group thanthe control group (P<0.01). Huo li su oral liquid unite tandospirong citrate capsule give quicker treatment than individually using unite tandospirongcitrate capsule effect is more obvious with fewer adverse reactions.Conclusions:1Epilepsy with anxiety in patients with anti-anxiety anxiety states likesignificantly reduced after treatment.2Epilepsy patients with anxiety anxioly therapy can significantlyimprove the quality of life of patients.3Treatment of epilepsy patients with anxiety application huo li su oralliquid unite tandospirong citrate capsule than separate unite flatness Law onecapsule effect is more obvious, and the rapid onset of adverse reactions.4Epilepsy with ant anxiety treatment of patients with anxiety shouldbecome the normal mode of treatment of such patients.