The Study On The Characteristics Of TCM Constitution In The Patients With Concomitant Essential Hypertension And Dyslipidemia

ObjectivesThrough the analysis of the distribution regularity of TCM constitution in the patients with concomitant essential hypertension and dyslipidemia and the correlation between constitution and the level of blood pressure, the level of blood lipid, risk factors, such as gender, age, smoking, body mass index, etc. This paper discusses the characteristics of TCM constitution, to provide evidents of the inervention of the diease for improving the level of syndrome differentiation and treatment.Methods417cases of patients with concomitant essential hypertension and dysli-pidemia were chosen to identify their TCM constitution, using the classifica-tion standard which was divided into nine kinds of constitution types by professor WangQi.To collect the data of the patients, such as general information, body mass index(BMI), blood pressure(BP), blood lipid including triglycerides (TG), total cholesterol(TC), low-density lipoprotein(LDL-C), high-density lipoprotein(HDL-C), apolipoprotein Al(Apo-Al), apolipoprotein B(ApoHB), lipoprotein(a)(LP(a)). Then analyzed the data collected above and also did the statistical analysis on the correlation between the risk factors and the TCM constitution by Logistic multiple regression analysis.Results1. There were35kinds of constitution were found from the417cases of patients with concomitant essential hypertension and dyslipidemia. Single constitution has163cases. Two kinds of constitution conbined has206 ases. Three kinds of constitution conbined has48cases. Phlegm-dampness constitution has102cases (24.46%).The Qi-deficiency conbined Phlegm-dampness constitution has59cases (14.15%). The Qi-deficiency conbined Blood-stasis constitution has43cases (10.31%).2. Essential hypertension merger dyslipidemia patients between the common type of constitution, the chi-square gender constitute more (P<0.01), age is a (P<0.01), body mass index by comparison between (P<0.01).3. Essential hypertension merger dyslipidemia patients classification and type of constitution is the relationship between hypertension level1> hypertension level2>hypertension level3, risk stratification and type of constitution of the relationship is high risk group>very high-risk group>threatened in the group, distribution difference are statistically significant (P<0.01, P<0.05). Different between systolic blood pressure level is the constitution (P<0.01), and diastolic blood pressure level comparison between (P>0.05).4. Essential hypertension merger dyslipidemia patients of constitution in Chinese medicine points to qualitative, due to a type of blood phlegmy wet, most of all, suggesting that three constitution for the disease the main type of constitution. Primary hypertension merger dyslipidemia more for mixed dyslipidemia, main performance in order to TC and LDL-C rise, TG, TC, and elevated LDL-C. The common type of constitution of dyslipidemia clinical classification than a comparison between (P<0.01). TG, TC, LDL-C, Apo-B level comparison between (P>0.05), hdl-c, Apo-Al, LP (a) level is (P<0.01).5. Essential hypertension merger dyslipidemia patients three common type of constitution and Logistic regression analysis of the risk factors, indicating that the men and normal size patients have the form of deficiency of trend; Youth, overweight patients have the form of phlegmy wet trend; Male patients have the formation of blood stasis trend.Conelusions1. Essential hypertension merger dyslipidemia patients of constitution in Chinese medicine points to qualitative, due to a type of blood phlegmy wet, most of all, suggesting that three constitutions for the disease the main type of constitution.2. The Phlegm-dampness type of constitution to the male patients with essential hypertension merger dyslipidemia take the largest proportion, and the Blood-stasis type of constitution to the female patients. Along with the increase of age, the conbined constitution becomes more and more.3. Essential hypertension merger dyslipidemia patients constitution with mild obesity is given priority to, and body mass index (BMI) of phlegmy wet with the highest level.4. Essential hypertension merger dyslipidemia patients each type of constitution are to hypertension grade1Lord; Qi and blood stasis due to quality, and blood phlegmy wet with very high-risk group of patients are more.5. Essential hypertension merger dyslipidemia patients with TC and LDL-C rise, TC and TG and LDL-C rise two kinds of dyslipidemia Lord; To phlegmy wet quality and clip phlegmy wet mass type of constitution of HDL-C is low. The Apo-Al of Phlegmy wet quality of patients is the lowest. The LP(a) of QI deficiency of patients is highest.