| 【 Objectives 】 Clinical to collect the second affiliated hospital of shandong university of TCM in May 2018 to December 2018 in the hospital,142 cases of hypertension level 3 combined dyslipidemia patient medical records,to the patients with the TCM constitution classification and decision table of questionnaire,a preliminary study of patients with hypertension level3 combined dyslipidemia physical distribution characteristics of traditional Chinese medicine and its correlation with clinical and biochemical indexes,hypertension combined with dyslipidemia prevention provide a theoretical basis.【Methods】(1)Select patients with grade 3 hypertension and dyslipidemia at the same time to carry out the "Chinese medicine constitution classification and judgment table"(see attached table 1)field questionnaire,according to the constitution criteria to score and determine the patient’s physique type;(2)Collect the general information of patients(gender,age,course of disease,family history,previous history,height,weight,hospital number,contact information,etc.),clinical biochemical indicators and auxiliary examination results;(3)Input all data into the EXCEL table,and use SPSS 22.0 to conduct statistical analysis of the patient’s physical distribution and clinical indicators.【Results】1.In this study,142 patients with hypertension level 3 combined dyslipidemia physical distribution from more to less is in turn: phlegmy wetmass 36(25.4%),hot and humid mass of 27(19.0%),20(14.1%)of the deficiency of qualitative,Yang 18(12.7%),15(10.6%),Yin deficiency,qi depression mass transfer 9(6.3%),gentle temperament,9(6.3%),blood stasis,7(4.9%),1(0.7%),the great mass.Due to the small number of patients with Yin deficiency,mild deficiency,blood stasis and idiocy,statistical analysis is not possible.Therefore,this study mainly discusses five constitutions:phlegm-dampness,dampness and heat,qi deficiency,Yang deficiency and qi stagnation.2.The levels of total cholesterol in different constitutions were successively from high to low: wet and hot substance > phlegm-wet substance >Yang deficiency substance > qi deficiency substance > qi stagnation substance.According to the statistical test,P = 0.001,the difference of total cholesterol distribution in patients with different constitutions was statistically significant.3.The levels of triglyceride in different constitutions were successively from high to low: phlegm-wet substance >,damp-hot substance >,qi-deficient substance >,qi-stagnation substance >,yang-deficient substance.After statistical test,P = 0.000,the difference of total cholesterol distribution in patients with different constitutions was statistically significant.4.The levels of low-density lipoprotein in different constitutions were successively from high to low: wet and hot substance > phlegm-wet substance >Yang deficiency substance > qi deficiency substance > qi stagnation substance.According to the statistical test,P = 0.001,the difference of total cholesterol distribution in patients with different constitutions was statistically significant.5.There were more males than females with abnormal HDL,and the difference was statistically significant.6.There was no statistical difference in the levels of high-density lipoprotein,fasting blood glucose and cystatin in different constitutions.7.Age,BMI,systolic blood pressure and diastolic blood pressure showed no statistical significance in different physical conditions.【Conclusions】1.In this study,the five main constitutions of patients with grade 3hypertension combined with dyslipidemia were phlegm-dampness,dampness and heat,qi deficiency,Yang deficiency and qi stagnation.2.Age,BMI,systolic blood pressure and diastolic blood pressure showed no statistical significance in different physical conditions.3.The differences of total cholesterol,triglyceride and low-density lipoprotein in different constitutions were statistically significant,while the levels of high-density lipoprotein,fasting blood glucose and cystatin in different constitutions were not statistically significant.It is considered to be related to clinical drug intervention and other reasons,but further research is needed.4.There were more males than females with abnormal HDL,and the difference was statistically significant.5.In this study,there were statistically significant differences in the distribution of total cholesterol in patients with grade 3 hypertension with dyslipidemia of different constitutions,and the total cholesterol level in patients with hot and humid temperament was the highest.The difference of triglyceride distribution in patients with grade 3 hypertension with dyslipidemia of different constitutions was statistically significant.There were significant statistical differences in the distribution of LDL in patients with grade 3 hypertension with dyslipidemia of different constitutions,and the LDL level was the highest in patients with hot and humid conditions. |