| BACKGROUNDEpilepsy is one of the common and frequently-occurring disease. It is estimated by the World Health Organization that there are about 50 million patients with epilepsy. The epidemiological data show that the prevalence is from 0.4% to 0.7% in China. Epilepsy is a disease caused by different factors, a chronic disorder due to the repeatedly excessive discharge of central nervous system, with the feature of paroxysmal, transient, repetitive, and rigidity, associated with various types of clinical seizures, epileptic waves showed in EEG and abnormalities of laboratory examination.The current treatment of epilepsy still mainly relys on the application of anti-epileptic drugs, lack of an ideal method to cure the disease. The quality of life in patients is the understanding of the impact brought by the illness and the treatment, reflecting differences between the actual situation and social relations, desire for physical and social psychology of the individuals. With the social progress and changes of medical mode in recent years, scientific research has gone beyond the sphere of mere biology, quality of life indicators has been increasingly token seriously. A number of studies reveal that epilepsy has a great impact on life quality of adult women patients. Self-efficacy is a powerful force in the operation of human behavior, which means the faith and confidence that people need to implement and complete a certain behavioral goal or to cope with a difficult situation successful. It plays an immeasurable and irreplaceable role in the control and regulation of behavior, especially in treatment and care process of chronic disease. The improvement of self-efficacy is conducive to the recovery of chronic disease. Therefore, making surveys and analysis of self-efficacy and factors influencing the quality of life of adult female patients with epilepsy, and then putting effective interventions for psychological problems, are of much social significance. At present, there are some researches and analysis in this regard, but studies special for of adult women are few. This study attempts to do related research and to make discoveries about the specificity of female adult patients, in order to provide theoretical basis accordingly focus on its health education, psychological interventions, the rehabilitation and improvement of life quality in adult female patients.OBJECTIVE1.Analysis the quality of life in adult female patients with epilepsy;2. Explore the main factors that impact of quality of life in adult female patients with epilepsy;3.Explore the correlation between self-efficacy and quality of life in adult female patients with epilepsy;4.Explore possible ways that can improve the quality of life in adult female patients with epilepsy.SUBJECT and METHODA total of 143 cases of adult female patients with epilepsy who receive treatment at Department of Neurology and EEG room, Qilu Hospital of Shandong University from March 2010 to December 2010 were enrolled in this study. Self-scale were used to survey the population and general sociological characteristics of patients. The "quality of life in epilepsy questionnaire (QOLIE-31)", "self-rating depression scale (SDS)", "self-Rating Anxiety scale (SAS)", "chronic disease self-efficacy scale" were used to assess the quality of life and self-efficacy in patients, and explores the influencing factors and the relationships between self-efficacy and quality of life.RESULTStatistical description and analysis of variance study revealed that these patients had almost no difference in age, seizure type, income, and education level. They had some difference in the course of the disease and occupations, though this difference had no statistical significance. There were significant differences in patients of different frequency in attack and this difference was statistically significant (P<0.05). Quality of life in female patients whose duration was more than a decade was significantly worse, patients who had paid employment had better quality of life, quality of life of patients whose seizure frequency was more than 1 time/month of was far worse than patients with lower seizure frequency. ANOVA analysis showed that quality of life scores in depression group and scores in all aspects were lower than non-depressed group, and the difference was statistically significant (P<0.001). Depression was the independent risk factor which leaded to the decline in quality of life of adult female patients with epilepsy. ANOVA analysis showed that the scores of anxiety group in the overall level of health, emotional health and social function were lower than non-anxious group, the difference was statistically significant (P<0.05).CONCLUSION1 Adult female patients with epilepsy overall live a low quality of life, in which the concerns of the onset, emotional health are the top two worst in eight areas of quality of life.Duration, occupation, seizure frequency have a close relationship with the quality of life in adult female patients. Among them seizure frequency significantly affects the quality of life.2 The incidence of depression and anxiety in adult female patients with epilepsy is higher than that in the normal population. Each of depression and anxiety is independent risk factor on quality of life, especially depression.3 The level of self-efficacy in adult female patients with epilepsy is in the mid to upper level, and self-efficacy is significantly affected by the kind of seizure.4 Self-efficacy has a wide correlation with all aspects of quality of life in adult female patients.5.Through the health education, the level of self-efficacy was improved and the quality of life was better than before. |