Objective: To investigate the effet of noninvasive bi-level positive airway pressure(BiPAP)ventilation in the treatment of patients with typeâ…¡respiratory failure due to acute exacerbations of chronic obstructive pulmonary disease (AECOPD) and varying levels of acute physiology and chronic health evaluationâ…¡(APACHEâ…¡)score.Methods: 60 cases of AECOPD with Typeâ…¡respiratory failure who received BiPAP were retrospectively viewed. Divide the cases into three groups (low-moderate-high)by the level of APACHEâ…¡score.Comparison was then made within the three groups for failure rate of BiPAP and the changes of arterial gas analysis ,hemogram and C-reactive protein(CRP).Result: Within 7 days of therapy the group of high-level of APACHEâ…¡score showed highest failure rate of BiPAP(35%),all the cases who had finished 7 days of BiPAP therapy showed significant improvement in blood gas analysis and CRP(P<0.05),no matter which group it belongs.Conclusion: BiPAP is an effective method to treat patitents with AECOPD complicated by typeâ…¡respiratory failure,and APACHEâ…¡can help to evaluate the disparity of treating effect of BiPAP.
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