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Epidemiologic Survey And Etiologic Study Of Brucellosis In Baicheng

Posted on:2008-05-25Degree:MasterType:Thesis
Country:ChinaCandidate:J G AnFull Text:PDF
GTID:2144360212996071Subject:Pathogen Biology
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Brucellosis (Brucella) is a aerobic Gram-negative Bacillus pumilis of the genus Brucella, is a disease of animals and human pathogens,and it not only are harmful to livestock production, but also seriously damage human health. Brucellosis disease (brucellosis), are also known as the Mediterranean remittent fever, Maltese fever, abortus fever or undulant fever. Brucellosis is systemic communicable disease troubled animal and human caused by the brucellar pathogens, and its clinical features of chronic fever, sweating, joint pain, hepatosplenomegaly, and so on. As Gram-negative Bacillus pumilis , much Brucella present globe, clubs and oval shape initial separation, so it was suggested that said "brucellosis". After serial subcultivation, the brucella present microsoma rod-shape, thallus of atrichosis, asporous form, and the capsule of virulent strain can be meager. WHO experts in 1985 divided brucellosis genus members into six types of bio-19. Clinically sheep, cows and pigs significance of the three bigger, sheep disease is the strongest. The variety of biological pathogens may was related with the occurrence of genetic variations adapted the pathogenic bacteria to the different host.Brucella has power vitality in a natural environment. In the secretion of the animals, excreta, and the organs of died animal, it can survive about four months , in some food about two months. Heat60°C 10-20 minutes or sunlight exposure, the bacteria could be killed, and it is more sensitive to the commonly used chemical disinfectants. Brucellosis disease is endemic throughout the world, according to survey the brucellosis occur in 123 countries of 160 countries worldwide. Our country is current in the pastoral areas of Inner Mongolia, Northeast, Northwest, and so on.(1) Source of infection: known to be 60 kinds of livestock, poultry, wildlife is the host of brucellosis. Is the principal source of human infection with sheep, cattle and pigs, and followed with dogs. First, the animal infected Brucella is contagious in the same animal species, causing infected or morbidity, and then spread to human beings.(2) Transmission:①infection by direct contact with skin and mucous;②gastrointestinal virus infection;③respiratory infections;④other flies carry and ticks bites, as well as the dissemination of the disease. But it is little importance.(3) Susceptible population: Human are easy susceptibility generally, and the disease will get a certain immunity, but there are different types of immune brucellosis, among 2~7% people who are infected again, and the residents of the affected areas can acquired immunity by hidden disease.(4) Epidemiological characteristics: This disease may incidence four seasons of one year, but for many seasons to livestock abortion. Its incidence is higher of agricultural areas than pastoral areas, and the rural areas than urban ones.In Jilin Province, Brucellosis incidence in recent years was upward trend and intensified epidemics among animals and humans, and its extent was gradually expanded, furthermore the outbreak and spread in some areas was also posture. Outbreak points, the incidence of new patients, typical symptoms of patients, the incidence of serious impact economic development on the region of morbidity. There is a change in the type of brucellosis in 1973-1998 compared with recent many years, and the type is mainly sheep1 brucellosis in Jilin Province in 1973-1998.Baicheng City of Jilin Province is the focus of outbreak and spread of the disease brucellosis. This paper was surveys and studies based on the 2005-2006 pandemic strain of the brucellosis in Baicheng, and it provide an important evidence a study of the development trend of brucellosis popular species in recent years, meanwhile, the epidemic disease prevention and control brucellosis in Baicheng important guiding significance.In this paper, the results are as follows :1. Through primary screening test and formal testing final diagnosised Brucellosis 265 cases in Baicheng during the period 2005 -2006, among the total the positive strain cultivated was 22 cases.2, Cultivated and compared the 22 were positive serum for the disease brucellosis strains with the preservation of international standard laboratory strain 16M bacteria sheep, cattle bacteria 544A, and breeds bacteria 1330S.3, The control results was : cattle strain type 1, type 1 6 strains sheep, goats 3 15 strains. The result exhibited epidemic strain during the period 2005-2006 in Baicheng is mainly sheep 3.
Keywords/Search Tags:Epidemiologic
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