| Objective: To investigate the effective mechanism and clinical significance of the prescription Mianyoufengfang(MYFF) on Seborrrheic Dermatitis.Methods:60 patients with seborrheic dermatitis were divided into two groups, Mianyoufengfang group (treatment group) and Weianzhi group(control group) at random. Seborrheic excrete rate(SER),the content of free fat acid(FFA) in sebum, the number of malassezia furfur baillon(M.furfur) on the nose were tested before and after treatment, and 10 normal controls were tested also, acting as normal compare group.In order to investagte the inhibition of MYFF on M.furfur. Juleps composed the prescription were alldecocted into solution, continuously diluted, the minimum inhibitory consistency of them were determined.Results:MYFF and Weianzhi both improved the symptoms, the effective rate of control group was 73.33%, and the treatment group was 90% which was significantly higher than that of the control group (P<0.01). SER, FFA, and number of M.furfur on the nose of treatment group were all decreased than those of before treatment(P<0.01). Polygonum cus pidatum,Coptis chinemsis,Rhaponticum uniflorum, Cimicifuga foetida, Biota orientalis,Rehmannia glutinosa,Paeonia suffruticosa, inhibited the multiplication of M.furfur.Conclusions:MYFF could inhibit secretion of sebaceous grands and propagation of M.furfur, so as to get rid of the two chief factor which caused seborrheic dermatitis. It had a reliably effect on seborrheic dermatitis. |
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