An Analysis Of The Current Situation And Factors Of Adverse Reaction

Purpose: 1 cases of adverse drug reactions were discovery in clinical Ruyijinhuang powder for external use, to explore its drug safety and to analyze the causes of adverse reactions.Material and method:This paper uses retrospective method analysis, the 6 adverse drug reactions reported in the past 30 years, the occurrence of adverse reactions of the drug is analyzed in detail; and in reference to the 2007 academician Zhang Boli in “the adverse reaction of traditional Chinese medicine and rational drug use”a book described Ruyi Jinhuang powder caused by allergic rash reports and web related content is a necessary complement. The composition, from Ruyijinhuang powder drug pharmacology, chemical components, quality control, the quality of drugs, the deployment of accessories, external use medicine and other aspects, discusses in detail the causes of adverse reaction of Ruyi Jinhuang powder, eventually forming the product processing method, allergy measures and ideas.Results: 1. Determine the Ruyi Jinhuang powder ADR treatment:For Ruyi Jinhuang powder caused by contact dermatitis and other adverse reactions of the disease, should be immediately discontinued, oral anti allergy drugs or topical steroid ointment, achieve anti allergy treatment effect. At the same time,the available 1:100 after dilution for patch test,through spot test results,clarify the allergen, prevent the recurrence of allergic reaction; 2.Through the analysis of related factors of adverse reaction of Ruyijinhuang powder, the specification of the preventive measures of adverse reactions, as follows:(1). Strengthen the clinical syndrome differentiation, adhere to the the principle of “Treatment based on syndrome differentiation”;(2).On relationship between Ruyijinhuang powder and its adverse reactions between the composition of smell and clinical application to pay attention to the history of allergy to inquiry answered pollen, Arisaema tuber, angelica and other herbs application;(3). To further improve the Ruyi Jinhuang powder quality control standards, especially to increase the toxic components of rhein, emodin, aloe emodin, different European decursin and limited requirements, reduce the incidence of adverse reactions;(4). Strengthen the original control and knowledge of traditional Chinese medicine knowledge positive propaganda, to avoid false advertising misleading adverse reactions caused by the incident;(5). Pay attention to Ruyi Jinhuang powder apply the batching water, sesame oil, vinegar, wine, honey in the external use, pay more attention to ask the patient’s allergy history, to honey tone deposited relatively safe;(6). The effect of Ruyi Jinhuang powder expression still need to further standardize and clear, usage of unknown “for external use”has become the underlying causes of adverse reactions occur.Conclusion: The adverse reaction of Ruyi Jinhuang powder case, from a multi-level and multi angle analysis the various causes of adverse reactions occur, refers to the all aspects of clinical concern and it is important to guide clinical rational drug use, to prevent adverse reactions.