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The Clinical Epidemiological Analysis Of Depressive Disorder So As To Discover The Syndrome Regularity

Posted on:2014-11-16Degree:DoctorType:Dissertation
Country:ChinaCandidate:H Y WangFull Text:PDF
GTID:1264330425958013Subject:Basic Theory of TCM
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Objective: to analyze the macroscopic symptom of the depressive disorder (slight ormidrange), the influential factor, the frequency and difference of symptom and thesyndrome regularity through the epidemiological cross-sectional study of the depressedpatients. We could clarify the syndrome regularity of the depressive disorder (slight ormidrange) and would explore the pathogenesis of the liver failing to control the dispersionand to accommodate the emotion. To provide the reference data for the treatment of thedepressive disorder (slight or midrange) the next phase, to add the fresh cognition so as toimprove and develop the treatment initiated from the liver.Methods: The epidemiological investigation was adopted to research the patients whowere diagnosed according to ICD-10and pop psychology measuring scale. Based on thedocuments and the combination of disease with syndrome, we have created the scheduletable and have finished the cases’ collection of the depressive disorder in ShandongProvince and Henan Province in the epidemiological cross-sectional study. We havegathered the syndrome and applied SPSS13.0software to analyze the data.Results:①Male115cases(36.3%)、Female202cases(63.7%), they are in the ratioof1∶1.76. The mean age is38years. During the cases,18years is the minimum and65years is the maximal. There are252cases (79.5%) whom have been married and48cases(15.1%) that were single. The education level: primary school142cases(44.8%)andcollege99cases(31.2%); Race: Han people314cases (99.1%);The occupation: thepeasants187cases (59.0%) and the students29cases (9.1%).②20psychiatric symptomswere investigated in the research. There was the frequency sequence of symptoms in thelight depressive disorder, such as thinking torpidity206cases (65.0%), hypoaction and hypologia (61.7%), the capability of society or economy decrease (60.1%),morbidforgetfulness (58.4%),anxiety (58.2%),visual hallucination and auditory hallucination(12.9%);There was the frequency sequence of symptoms in the midrange depressivedisorder, such as emotion drawdown129cases (40.7%), depress(38.1%),afraid and pavor(31.5%), defatigation (31.2%),interest degrades(27.9%), visual hallucination and auditoryhallucination(3.5%). There were25somato-symptoms in the depressive disorder. Therewas the frequency sequence of symptoms in the light depressive disorder, such as dizziness148cases (46.6%), shortness of breath(44.6%), sore and weak loins and knees (43.9%),dry mouth and dry swallow (43.6%), palpitation (41.4%), debility sexualis42cases(13.4%); There was the frequency sequence of symptoms in the midrange depressivedisorder, such as sigh77cases (24.3%), dry mouth and dry swallow (17.5%),dizziness(16.6%),anorexia(12.9%),palpitation and sore and weak loins and knees (11.4%),dizziness(1.2%).③Tongue demonstration and pulse tracings: The colour of tongue:carnation tongue157cases (49.5%)、pale tongue69cases (21.8%)、red tongue50cases(15.8%); The lingual contour: normal tongue213cases (67.2%)、teeth-marked tongue61cases (19.2%)、swollen tongue50cases (15.8%); The colour of coated tongue: whitecoating133cases (42.0%)、light yellow coating65cases (20.5%) and light white coating63cases (19.9%); The appearance of coated tongue: thin coating139cases (43.8%)、 thickcoating127cases (40.1%)、 greasy coating118cases (37.2%); The pulse tracings: wirypulse211cases(66.6%)、sunken pulse107cases (33.8%)、slippery pulse97cases (30.6%)、thready pulse89cases (28.1%)、frequent pulse46cases(14.5%).④There were significantdifference on the gender for the patients who had educational level and marriage. Therewas statistical significance for the patients who had different gender (P<0.05or P<0.01);There wasn’t significant difference on the pattern of syndrome of the gender. We havefound frequently four syndrome differentiations in the investigation such as stagnation ofliver-QI, deficiency of both heart and spleen, stagnation of liver-QI and stagnation ofphlegm, stagnation of liver-QI with deficiency of the spleen.⑤We discovered the most principal syndrome was stagnation of liver-QI,146cases(46.1%) in the investigation. For the rest stagnation of liver-QI and stagnation ofphlegm59cases (18.6%), stagnation of liver-QI with deficiency of kidney22cases (6.9%),stagnation of liver-QI with deficiency of the spleen15cases (4.7%), deficiency of both heart and spleen14cases (4.4%). There were some symptoms included in the principalsyndrome regression equation through the logistic multiple regression analysis. Stagnationof liver-QI: anxiety, short breath, sunken pulse and frequent pulse, light yellow tonguecoating; stagnation of liver-QI and stagnation of phlegm: thinking torpidity, dementia,globus hystericus, gloomy tongue, thick and greasy tongue coating, smooth pulse;stagnation of liver-QI with deficiency of kidney: night-sweat, tinnitus, insomnia, wirypulse; stagnation of liver-QI with deficiency of the spleen: pessimistic, dryness of eye,distension and fullness of gastric cavity, loose stool, swollen tongue,white coating, threadypulse; deficiency of both heart and spleen: dementia, insomnia, light white tongue,swollen tongue,delicate pulse.Conclusion:①The disease incidence of the depressive disorder was high in thepatients who was female, married or single, infra-primary school or super-college, peasantand student.②There were significant difference on the gender for the patients who hadeducational level and marriage. There was statistical significance for the patients who haddifferent gender.③There was no significant difference on the gender for the principalsyndrome. We have found frequently four syndrome differentiations in different regionssuch as stagnation of liver-QI, deficiency of both heart and spleen, stagnation of liver-QIand stagnation of phlegm, stagnation of liver-QI with deficiency of the spleen.④Thediagnosis of the depressive disorder include the central symptom, psycho-symptom andsomato-symptom. Depression, interest degrades and anhedonia were the central symptomof the depressive disorder. The key pathogenesis of the depressive disorder is stagnation ofliver-QI, which is the misalignment of liver controlling the dispersion and accommodatingthe emotion. The principal syndrome of the depressive disorder in TCM was stagnation ofliver-QI, which was located and initiated from the liver. There were four syndromedifferentiations frequently for example stagnation of liver-QI with stagnation of phlegm,stagnation of liver-QI with deficiency of kidney, stagnation of liver-QI with deficiency ofthe spleen, deficiency of both heart and spleen.⑤The logistic multiple regression analysisshowed the different syndrome have various principal symptoms. Stagnation of liver-QI:anxiety, short breath, sunken pulse and frequent pulse, light yellow tongue coating;stagnation of liver-QI and stagnation of phlegm: thinking torpidity, dementia, globushystericus, gloomy tongue, thick and greasy tongue coating, smooth pulse; stagnation ofliver-QI with deficiency of kidney: night-sweat, tinnitus, insomnia, wiry pulse; stagnation of liver-QI withdeficiency of the spleen: pessimistic, dryness of eye, distension and fullness of gastriccavity, loose stool, swollen tongue,white coating, thready pulse; deficiency of both heartand spleen: dementia, insomnia, light white tongue, swollen tongue,delicate pulse.
Keywords/Search Tags:the depressive disorder, the epidemiological investigation, the syndromeregularity, liver controlling the dispersion, liver accommodating the emotion, stagnationof liver-QI
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