| Purpose:Observe the clinical efficacy of treating obstructive acute gastritis with Naked Flower Purple Bead particles in patients with damp-heat type,and evaluate its therapeutic effectiveness.Material and method:A total of 75 patients with acute gastric obstruction type of damp-heat syndrome who were admitted to the emergency department of Liaoning University of Traditional Chinese Medicine Affiliated Hospital from January 2022 to September 2022 were included in the study.The experimental group(Naked Flower Purple Bead granule combined with Epprazole sodium group)and the control group(Epprazole sodium group)were randomly divided into 50 and 25 cases in a ratio of 2:1.The patients were treated for one week.The single-item scores,total scores,and syndrome efficacy of the traditional Chinese medicine symptoms of upper abdominal pain,upper abdominal distension,nausea and vomiting,belching,and decreased appetite were compared before and 4 days and 7 days after treatment between the two groups.Blood routine tests,including white blood cell count and neutrophil count,and C-reactive protein(CRP)were compared before and after treatment between the two groups.Statistical methods: SPSS 23.0 statistical analysis software was used to analyze the data obtained in this study.If the measurement data conformed to normal distribution and had homogeneity of variance,analysis of variance(ANOVA)was used,while Kruskal-Wallis H test was used if the data did not conform to normal distribution or had inhomogeneity in variance.Mann-Whitney U test was used for group comparison.Chi-square test was used for counting data,and rank sum test was used for ordinal data.A P value less than 0.05 was considered statistically significant.Results:1.Collect 75 cases,among which 3 cases were lost,with 2 cases lost in the experimental group and 1 case lost in the control group.In the end,72 cases were included,with 48 cases in the experimental group and 24 cases in the control group.On the 4th day,7 cases were cured in the experimental group,and basic information was excluded during the statistics on the 7th day.2.Traditional Chinese medicine symptom scores: For the five symptoms of upper abdominal pain,upper abdominal distension,nausea and vomiting,belching,and decreased appetite,the experimental group had greater improvement than the control group on the 4th day after treatment,and the difference between the two groups was statistically significant(P<0.05).For the four symptoms of upper abdominal pain,upper abdominal distension,belching,and decreased appetite,the experimental group had greater improvement than the control group on the 7th day after treatment,and the difference between the two groups was statistically significant(P<0.05).The improvement in nausea and vomiting symptoms was the same in both groups,and the difference between the two groups was not statistically significant(P>0.05).The experimental group and the control group had statistically significant differences in these five symptoms before treatment and on the 4th and 7th day after treatment,respectively(P<0.05).The total scores of both groups also had similar results.3.Traditional Chinese medicine syndrome efficacy: The overall effective rate of the experimental group and the control group on the 4th day after treatment was 90% and 36%,respectively,and the difference between the two groups was statistically significant(P<0.01).The overall effective rate of the experimental group and the control group on the 7th day after treatment was 97.5% and 62.5%,respectively,and the difference between the two groups was statistically significant(P<0.01).3.Physical and chemical indicators: The experimental group had better improvement in white blood cell count and neutrophil count,and CRP count on the 4th day after treatment than the control group,and the difference between the two groups was statistically significant(P<0.05).The experimental group and the control group had statistically significant differences in these three indicators before treatment and on the 4th day after treatment,respectively(P<0.05).Conclusion:1.The Naked Flower Purple Bead granule group(experimental group)is more effective in improving AG pain than the Epprazole sodium group(control group).2.The Naked Flower Purple Bead granule group(experimental group)is more effective in relieving upper abdominal distension,nausea and vomiting,belching,and decreased appetite symptoms than the Epprazole sodium group(control group).3.The Naked Flower Purple Bead granule group(experimental group)is more effective in anti-infection than the Epprazole sodium group(control group). |
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