Observation On The Efficacy Of The Qi-regulating, Tan-removing And Cough-clearing Recipe In The Treatment Of Cough Variant Asthma With Qi Stagnation And Phlegm Stagnation Syndrom

Objective: The purpose of this study is to objectively evaluate the clinical effect of liqi Qutan Zhike prescription on the treatment of cough variant asthma by observing the curative effect of qi stagnation and phlegm stagnation syndrome,and to provide new ideas and evidence-based basis for the clinical treatment of cough variant asthma in the future.Methods: A total of 62 patients were included in this study,all of whom met the inclusion criteria and visited the outpatient and inpatient departments of respiratory and critical care medicine in Changde First Hospital of Traditional Chinese Medicine from December 2020 to December 2021.Using random number table method,31 patients were randomly divided into control group and treated with budesonide formoterol powder inhalation alone.In the treatment group,31 patients were treated with liqi expectorant cough decoction combined with budesonide formoterol powder inhalation.The treatment course was 4 weeks.The scores of daytime and night cough,total score of main cough symptom,score of secondary cough symptom,Lecester cough quality of life Questionnaire score(LCQ),VISUAL analog scale(VAS)score,daily variation rate of peak expirative flow rate(PEF),clinical comprehensive efficacy,recurrence rate and adverse reactions were compared in detail between the two groups before and after treatment.SPSS28.0 software was used for data analysis and processing.Results: A total of 62 patients were included in this study,including 2 cases of withdrawal,shedding and termination during treatment.1.Before treatment,the two groups were compared in terms of gender,age,course of disease,daytime and night cough score,total cough symptom score,Chinese medicine sub-symptom correlation score,Leicester cough quality of life Questionnaire score(LCQ),VISUAL analog scale score,daily variation rate of expiratory peak flow rate(PEF),etc.(P >0.05);2.The scores of daytime and night cough,total score of primary cough symptom and related score of TCM secondary symptoms were compared between the two groups after treatment;The scores of daytime and night cough,total score of main symptom and TCM secondary symptom in treatment group were significantly lower than those in control group(P < 0.05).3.LCQ score,VAS score and PEF value were compared between the two groups;VAS score,LCQ score and PEF value in treatment group were significantly lower than those in control group(P < 0.05);4.The total effective rate of clinical comprehensive efficacy was 90% in the treatment group and 76.7% in the control group,which was significantly higher than that in the control group(P < 0.05).5.The recurrence rate of the two groups was statistically analyzed(P < 0.05).Conclusion: Liqi Expectorant cough decoction combined with budesonide formoterol powder inhalation and budesonide formoterol powder inhalation are effective in treating QI stagnation and phlegm stagnation syndrome of CVA.The treatment group was significantly better than the control group in improving the scores of daytime and night cough,total score of main cough symptom,TCM sub-symptom score,LCQ score,VAS score and PEF value.The treatment group can not only effectively relieve the clinical symptoms of CVA patients with qi stagnation and phlegm depression,but also have low recurrence rate and fewer adverse reactions,which is worthy of clinical application and promotion.