Comparison Of The Diagnostic Value Of 2D TSE And 3D SPACE Sequence In Preoperative T Staging Of Rectal Cancer

Purpose:To compare the diagnostic value of three-dimensional variable rotation angle isotropic fast spin echo(3D SPACE)sequence and traditional two-dimensional fast spin echo(2D TSE)sequence in preoperative T staging of rectal cancer.Materials and Methods:A total of 75 patients with rectal cancer who were treated in our hospital from January 2018 to December 2019 were selected.The patients underwent 2D TSE and 3D SPACE sequence scans before surgery.Image quality was evaluated by calculating the SNR,CNR and image score of 2D TSE and 3D SPACE sequence images.The postoperative pathological results were used as the gold standard.To compare the accuracy of 2D TSE and 3D SPACE sequences in diagnosing preoperative T staging of rectal cancer.Results : SNR of 2D TSE and 3D SPACE sequences were as follows: tumor(83.94±40.34 vs.119.95±39.83,p=0.016),fat(213.56±95.26 vs.191.22±59.47,p=0.43),muscle(41.86±19.34 vs.40.40±15.58,p=0.82).CNR were respectively(19.36±10.11 vs.27.54±18.72,p=0.14).Image quality scores were as follows: rectal mucosa(3.00(2.00,3.00)vs.3.00(3.00,3.00),p=0.013),rectal muscularis propria(3.00(2.00,3.00)vs.3.00(3.00,3.00),p=0.001),rectal serosa or rectal adventitia(3.00(2.00,3.00)vs.3.00(3.00,3.00),p=0.99),perirectal fat(3.00(3.00,3.00)vs.3.00(3.00,3.00),p=0.80),mesorectal fascia(3.00(3.00,3.00)vs.3.00(3.00,3.00),p=0.21),tumor(3.00(3.00,3.00)vs.3.00(3.00,3.00)p=0.99).For tumors,SNR of 3D SPACE sequences were superior to 2D TSE.For fat and muscle,there were no statistical difference in SNR,CNR between 2D TSE and 3D SPACE sequences.Compared with postoperative pathological results,the diagnostic consistency of 2D TSE sequence(Kappa=0.494,p<0.001)was lower than that of 3D SPACE sequence(Kappa=0.95,p<0.001).Respectively,the diagnostic accuracy rates for T staging were 76.00% and 98.67%.Conclusion:2D TSE are as reliable as 3D SPACE sequences in displaying the rectal serosa or rectal adventitia,perirectal fat,mesorectal fascia,and tumor.3D SPACE sequence are better for displaying rectal mucosa and rectal muscularis propria.For preoperative T staging of rectal cancer,3D SPACE sequence has higher diagnostic accuracy than traditional HR 2D TSE sequence,which can better provide imaging basis for clinical treatment plan.