Prediction Of HEART Score Combined With Hypersensitive Troponin T 0/2 Hour Detection In Emergency Chest Pain Patients

Objective:To explore the correlation between plasma hypersensitive troponin T(hs-Tn T)level and HEART score and risk stratification in patients with acute chest pain.To analyze the predictive value of hs-Tn T combined with HEART score in the diagnosis and prognosis of emergency chest pain patients.Methods:This study is a Prospective cohort study.300 patients with acute chest pain who met the inclusion criteria were selected from the emergency department of the affiliated hospital of Inner Mongolia Medical University in Inner Mongolia from May 2022 to December 2022.Serum hs Tn T was detected by electrochemiluminescence immunoassay after admission.Use HEART score to score patients with chest pain and determine their risk stratification.Then,follow-up statistics were conducted on the occurrence of cardiovascular adverse events within30 days,and further analysis was conducted on the relationship between hs-Tn T levels and HEART risk stratification in patients.Using Excel to input data and SP-SS26.0 software for statistical analysis,P<0.05 indicates a statistically significant difference.Results:1.According to the follow-up results,the patients were divided into a control group and an observation group.The control group: the patients had no cardiovascular adverse events within 30 days of onset,while the observation group: the patients had cardiovascular adverse events within 30 days of onset.Comparing the evaluation data of the two groups of patients,the results showed that there were significant differences in the levels of D-dimer,troponin T,and Killip grading between the two groups of patients(P<0.05).2.According to the results of the HEART score,the patients were divided into three groups: low risk,medium risk,and high risk.(1)There were significant differences in data such as hypersensitive troponin T,D-dimer,and Killip grading among the three groups(P.Among them,10(14.93%)cardiovascular adverse events occurred in the low risk group,15(9.94%)cardiovascular adverse events occurred in the medium risk group,and 40(48.78%)cardiovascular adverse events occurred in the high risk group.There were significant differences among the three groups(P<0.05),indicating a positive correlation between HEART score and the incidence of cardiovascular adverse events within 30 days The level of hypersensitive troponin T in patients in the three groups was lower in the low risk group than in the medium risk group and higher in the high risk group(P<0.05).3.Patients were divided into 4 intervals based on the level of hypersensitive troponin T,and there were significant differences between the four groups in terms of age,length of stay,D-dimer,and Killip grade(P<0.05);The number of adverse cardiovascular events in Q1,Q2,Q3,and Q4 groups was 2,6,19,and 38,respectively.There was a significant difference between the four groups(P<0.05).4.A bivariate correlation analysis was performed between the HEART score and the level of hypersensitive troponin T in all enrolled patients.The results showed that there was a positive correlation between the serum level of hypersensitive troponin T and the HEART score(r=0.262,P<0.001).5.The ROC curve was used to analyze the value of HEART score and hypersensitive troponin T in evaluating cardiovascular adverse events in CCP patients within 30 days of onset.The results showed that the area under the curve(AUC)of hs-Tn T for MACE in CCP patients within 30 days of onset was 0.919(95% CI 0.882 to 0.947).The area under the curve(AUC)of the HEART score for MACE in emergency chest pain patients within 30 days of onset was 0.880(95% CI 0.837 to 0.914).6.Using SPSS 26.0 statistical software to map the ROC of the combination of HEART score and hypersensitive troponin T in assessing cardiovascular adverse events in CCP patients within 30 days of onset.The results suggest that the AUC of the combination of HEART score and hypersensitive troponin T in assessing cardiovascular adverse events in CCP patients within 30 days of onset is 0.954(95% CI 0.923-0.975).Conclusion:1.Hypersensitivity troponin T level is positively correlated with HEART score.The combination of the two can effectively improve the predictive value of early diagnosis and MACE within 30 days after the onset of CCP.2.HEART score can be used as an independent predictor of risk factors in patients with cardiogenic chest pain;It can effectively predict the risk of cardiovascular adverse events in CCP patients within 30 days of onset.3.The level of hypersensitive troponin T is directly related to the risk of cardiovascular adverse events in CCP patients within 30 days of onset,and can be used to predict cardiovascular adverse events in CCP patients within 30 days of onset.