The Study On Risk Factors And Syndromic Factors Of Recurrent Cardiovascular Events After PCI With LDL-C Standard

Objective: To explore the correlation between the remaining risk factors except LDL-C and TCM syndrome types in patients with coronary heart disease with low density lipoprotein cholesterol < 1.8mmol/L after PCI and the recurrence of cardiovascular events,so as to provide some reference for TCM prevention and treatment of recurrence of cardiovascular events after PCI.Methods: By retrospective analysis,247 patients from Heart Disease Center,Heart Health Center,and the Third Clinical Hospital of Changchun University of Traditional Chinese Medicine who met the inclusion criteria of this study were selected from the outpatient department and treatment area of cardiovascular medicine in the Affiliated Hospital of Changchun University of Traditional Chinese Medicine.General data,physical and chemical examination results,tongue and pulse symptoms on admission were analyzed.After normative data,SPSS 26.0 software was used for statistical analysis,and the distribution rules of syndrome elements and syndrome types of recurrent cardiovascular events after PCI were summarized,and the correlation between them and various risk factors was analyzed.Results:1.The most common syndromes of this disease are blood stasis > Qi deficiency >phlegm turbidity > Qi stagnation.The most common TCM syndromes are qi deficiency and blood stasis syndrome > Qi deficiency and Yin deficiency syndrome > phlegm turbidity and internal obstruction syndrome.2.There were significant differences in age among the syndrome types(P<0.05).There were significant differences in age between the four groups of heart-kidney Yang deficiency and Qi deficiency and blood stasis,phlegm turbidity and internal obstruction,Qi stagnation and blood stasis,cold coagulation and heart-pulse syndrome,and Qi stagnation and blood stasis and Qi Yin deficiency.3.There were significant differences in the distribution of smoking history between phlegm-turbidity syndrome and non-turbidity syndrome(P<0.05).There were significant differences between the syndrome of Qi deficiency and blood stasis and the syndrome of phlegm turbidity and internal obstruction in the distribution of drinking history(P<0.05).4.There were significant differences in UA among the syndrome types(P<0.05).There were significant differences between the syndrome of phlegm-turbidity internal obstruction and the syndrome of Qi deficiency and blood stasis,the syndrome of Qi deficiency and Qi deficiency and the syndrome of heart-kidney Yang deficiency(P<0.05).There were significant differences between Qi-Yin deficiency syndrome and non-Qi-Yin deficiency syndrome,and between phlegm-turbidity internal obstruction syndrome and non-phlegm-turbidity internal obstruction syndrome in the distribution of abnormal UA(P<0.05).5.There were significant differences in TG among the syndrome types(P<0.05),and there were significant differences between the phlegm-turbidity internal obstruction syndrome and the deficiency of Qi and Yin,and the deficiency of heart-kidney Yang syndrome(P<0.05).6.There were significant differences in Hcy among the syndrome types(P<0.05),there were significant differences between Qi deficiency and blood stasis syndrome and Qi Yin deficiency syndrome(P<0.05),and there were significant differences between phlegm-turbidity and internal obstruction syndrome and Qi Yin deficiency syndrome and heart-kidney Yang deficiency syndrome group(P<0.05).There were significant differences in the distribution of abnormal Hcy between turbidity-internal obstruction syndrome and non-turbidity-internal obstruction syndrome(P<0.05).7.There were no significant differences in gender,hypertension,diabetes,time after PCI,TC,HDL-C,hs-CRP among all syndrome types(P>0.05).Conclusion: The most common TCM syndromes for recurrent cardiovascular events after PCI are blood stasis,qi deficiency,phlegm turbidity and qi stagnation,and the most common TCM syndromes are qi deficiency and blood stasis,qi deficiency and Yin deficiency,and phlegm turbidity and internal obstruction.Each syndrome type had significant differences with age,UA,TG and Hcy levels,and significantly different from smoking,drinking,abnormal UA and abnormal Hcy distribution,which could be used as a reference for TCM syndrome differentiation.