Correlation Analysis Of Neutrophil/Lymphocyte Ratio,Platelet/Lymphocyte Ratio And Left Ventricular Hypertrophy In Patients With Essential Hypertension

Objective:To investigate the correlation between neutrophil/lymphocyte ratio(NLR)and platelet/lymphocyte ratio(PLR)and left ventricular hypertrophy(LVH)in patients with essential hypertension.Methods:Using a retrospective analysis,a total of 135 patients with primary hypertension from January 2020 to December 2021 in the cardiology treatment area of Jilin FAW General Hospital and Jilin Provincial People’s Hospital were selected.General clinical data,laboratory tests and echocardiographic indices of the patients were collected,and the left ventricular myocardial mass index(LVMI)was calculated.The patients were divided into LVH group(n=51)and non-LVH group(n=84)according to the diagnostic criteria of LVH.SPSS26.0 software was applied to statistically analyze the correlation between NLR and PLR and LVH in patients with essential hypertension.Results:Compared with the non-LVH group,the history of alcohol consumption,systolic blood pressure,white blood cell count,NLR,fasting glucose and uric acid levels were significantly higher in the LVH group,with statistically significant differences(P<0.05);Spearman’s correlation analysis showed that hypertension classification,systolic blood pressure,white blood cell count,NLR,fasting glucose,uric acid and urea nitrogen levels were positively correlated with LVMI(r_s=0.197,0.293,0.192,0.171,0.211,0.190,0.228,P<0.05)and triglyceride levels were negatively correlated with LVMI(r_s=-0.204,P<0.05);multifactorial logistic regression analysis showed that the effects of history of alcohol consumption,systolic blood pressure and NLR on LVH in patients with essential hypertension were statistical significance(OR=3.27,1.03,1.31,95%CI 1.18-9.04,1.00-1.05,1.01-1.70,P<0.05).PLR has not been found to be independently associated with LVH in patients with essential hypertension.Conclusion:NLR levels were significantly higher in patients with primary hypertension LVH compared with those without LVH;NLR levels were positively correlated with LVMI in patients with essential hypertension;and NLR was an independent risk factor for LVH in patients with primary hypertension.PLR has not been found to be independently associated with LVH in patients with essential hypertension.