| Objective:The purpose of this study was to investigate the effect of acupoint electroacupuncture(EA)on postoperative insomnia quality and serum melatonin level in patients with intestinal cancer,and to explore the preventive effect of EA on postoperative insomnia in patients with intestinal cancer.Methods:A total of 70 patients with colorectal cancer scheduled for laparoscopic radical resection in the Department of Surgery of the People’s Hospital affiliated to the People’s Fujian University of Traditional Chinese Medicine hospital were randomly divided into control group and trial group,35 patients in each group.Both groups were treated with conventional treatment of colorectal cancer.In the experimental group,conventional treatment of colorectal cancer and electroacupuncture was applied at Acupoints Baihui,shenting,bilateral Shenmen and bilateral Sanyinjiao at 1 day before surgery,on the day of surgery and 1 ～ 5 days after surgery,the patients in the control group were not treated with electroacupuncture,while those in the control group were not treated with electroacupuncture.The Pittsburgh Sleep Quality Index(PSQI)and Athens insomnia scale(AIS)scores were compared before surgery(T0),on the first day after surgery(T1),on the sixth day after surgery(T2)and on the fourth week surgery(T3),the levels of serum melatonin(MT)were measured before surgery(T0)and 6 days after surgery(T2).To investigate the preventive effect of perioperative electroacupuncture on postoperative insomnia(PID)in patients undergoing radical surgery for intestinal cancer.Results:1.General information: there were no significant differences in sex,ASA grade,age,height and weight between the two groups(P>0.05).2.Sleep parameters:(1)The incidence of PID was significantly lower at T1 and T2 than that in the control group(P<0.05).At T0 and T3,there was no significant difference between the two groups(P>0.05).(2)PSQI score: At T0,there was no significant difference in PSQI score between the two groups(P>0.05).After EA intervention,the PSQI scores of T1 and T2 were higher than those of T0,at T1 and T2,the PSQI score of the experimental group was significantly lower than that of the control group(P<0.05).While at T3,there was no significant difference between the two groups(P>0.05).(3)AIS score: At T0,there was no significant difference in AIS score between the two groups(P>0.05).After EA intervention,the AIS scores of T1 and T2 were significantly higher than those of T0 in both groups,and the AIS scores of T1 and T2 were significantly lower than those of the control group(P<0.05).While at T3,there was no significant difference between the two groups(P>0.05).(4)MT Concentration: At T0,there was no difference in MT concentration between the two groups(P>0.05).At the end of EA intervention,the MT concentration of T2 in both groups was lower than that at T0,and the concentration of MT in experimental group was higher than that in control group,the difference was statistically significant(P<0.05).4.Postoperative factors:(1)VAS score: At T1,there was no significant difference in Vas score between the two groups(P>0.05).At T2,The VAS score of the experimental group was lower than that of the control group,the difference was statistically significant(P<0.05).(2)Other factors: There was no significant difference in the operative time,propofol,remifentanil,dexmedetomidine,blood loss,fluid replacement and the cases of postoperative infection,nausea and vomiting between the two groups(P>0.05).The number of cases taking sedatives and sleeping pills in the experimental group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Electro-acupuncture at acupoints during perioperative period can decrease the PSQI and AIS scores,promote the expression of MT,decrease the VAS scores of pain,improve the sleep quality of patients and reduce the occurrence of PID,electro-acupuncture intervention can prevent the occurrence of PID. |
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