| Objective: To analyze the correlation between BMI and 25-hydroxyvitamin D,and to understand the nutritional status of vitamin D in children in water area and analyze its characteristics and influencing factors,so as to provide evidence for clinical rational vitamin D supplement and maintain healthy body posture.Methods: A total of 805 children aged 0-12 who underwent physical examination in the outpatient Department of Child Health Care,the Second and Seventh Affiliated Hospital of Xinjiang Medical University from December 2020 to December 2022 were selected as subjects according to inclusion and exclusion criteria.The parents of the selected children filled in the questionnaire.According to the BMI recommended by WHO,the children were divided into three groups: normal group,lean group and overweight group.Venous blood was extracted on an empty stomach in the morning,and the concentration of 25-(OH)D in serum was determined by chemiluminescent particle immunoassay.Statistical software was used to analyze and compare the serum 25-(OH)D levels,different 25-(OH)D levels and the analysis of daily lifestyle factors in children of different genders,different age groups,different BMI groups and different seasons.Results: 1.General conditions:Among the 805 children,473 were boys,accounting for 58.76%;332 cases were girls,accounting for 41.24%;There were 390 cases(48.45%)in lean group,321 cases(39.88%)in normal group and 94 cases(11.68%)in obese group.(2)The average level of serum25-hydroxyvitamin D in the 805 children was(25.06±12.64)ng/m L,and the rate of sufficiency,insufficiency,deficiency,severe deficiency and excess was 30.43%,29.57%,32.55%,7.08% and 0.37%,respectively.(3)The 25-(OH)D levels of boys and girls were(23.05±13.15)ng/m L and(25.06±12.31)ng/m L,respectively,with no significant difference(P > 0.05).(4)Compared with different BMI and serum 25-hydroxyvitamin D,the normal group had the highest average level of(28.39±14.68)ng/m L,the wasting group had the highest average level of(25.76±12.35)ng/m L,and the obese group had the lowest average level of(22.51±10.88)ng/m L.The difference between any two groups was statistically significant(P < 0.05).(5)Among different age groups,the infant group was the highest[(31.96±11.00)ng/m L];The infant group was(29.50±14.21)ng/m L,there was significant difference between the two groups(P < 0.05).The serum level of preschool children was(22.51±9.62)ng/m L,which was significantly lower than that of infants and young children.The level in school-age group was(15.93±8.36)ng/m L,and there was significant difference between the groups(P < 0.05).(6)The average serum 25-(OH)D level of children in spring,summer and autumn was(23.61±11.58)ng/m L,(28.21±14.75)ng/m L and(25.88±12.80)ng/m L,respectively.In winter,it was(22.80±10.47)ng/m L,and there was significant difference between any two groups(P < 0.05).Conclusions: 1.The overall level of serum 25(OH)D in children in the water district of Urumqi was low,especially in children aged 6-12 years.2.There was a significant negative correlation between BMI and serum 25(OH)D level.The greater the BMI,the greater the probability of obesity,and the lower the serum 25(OH)D level,suggesting a vicious circle between obesity and vitamin D deficiency.3.The serum 25(OH)D level of children in Wushi water district decreased with age.4.Children of all ages need to appropriately increase outdoor activities and reasonable vitamin D supplementation,especially school-age and preschool children.Vitamin D supplementation should be appropriately increased in autumn and winter.Vitamin D health education needs to be further promoted. |
