| Background and purpose: Cerebral infarction is a series of cerebrovascular diseases with limb,speech function and psychological dysfunction caused by cerebral cell ischemia,hypoxia and necrosis due to intracranial thromboembolism or insufficient cerebral blood supply.The disability rate of ischemic stroke is as high as 70%～80%,of which50%～70% is left with obvious disability.The incidence rate of post stroke depression(PSD)can reach 18%～33%.However,the traditional rehabilitation treatment has poor effect on negative emotions such as limb activity disorder,post-stroke anxiety and depression after cerebral infarction.Mindfulness originates from Eastern Buddhism,but it is not a religion.It exposes its feelings through mindfulness meditation and other training,and enters the mindfulness state through self-management,relaxation and acceptance.Mindfulness based therapy(MBT)is a modern psychological therapy developed by scholars such as Joe Kabagin on the basis of mindfulness theory.Mindfulness therapy can enhance people’s concentration on themselves,improve the body’s tolerance for pain,and reduce the impact of negative emotions(anxiety,depression,etc.)on psychology.Because mindfulness therapy has great benefits for cognitive change and emotional regulation by focusing on the present to improve body control and not judging,MBT is currently widely used in clinical practice.However,some surveys showed that the volume of the anterior cingulate gyrus and insula of the elderly did not change significantly after 18 months of meditation intervention;The difference of perfusion between groups also did not reach statistical significance,and the research on MBT treatment of hemiplegia after cerebral infarction was not sufficient.Therefore,this study applied mindfulness therapy to patients with hemiplegia and negative emotions(anxiety,depression)after cerebral infarction,and observed and studied the changes of limb activity and mental state of patients.The results are as follows.Objective:To observe the effects of mindfulness treatment on patients with cerebral infarction.Methods:Sixty-six patients with acute cerebral infarction and hemiplegia admitted to our hospital from October 2021 to December 2022 were selected.The patients had no anxiety and depression before the onset of the disease and had negative emotions after the onset of the disease(HAMA score of7-20 points,SDS score of 40-62 points).They were randomly divided into two groups,including 33 in the study group and 33 in the control group.There were 3 cases of missing data,and the remaining 63 cases.The general data(age,sex,past medical history,smoking and drinking history)of the patients in the test group and the control group were compared,and the difference was not statistically significant(P>0.05),which was comparable.SPSS25.0 software was used for statistical analysis.The measurement data were expressed in ?±s according to the normal distribution,and the median and interquartile spacing were expressed according to the non-normal distribution.The comparison between the two groups that were consistent with the normality and the homogeneity of variance was performed using t test,and the single factor square difference analysis was used for the three groups and above.The non-parametric rank sum test was used for the non-conformity with the normality and the homogeneity of variance,P<0.05 was statistically significant.Results:1.Comparison of baseline data: A total of 63 patients completed the trial,and there was no statistically significant difference between the baseline values of the two groups(P>0.05).2.Comparison of results between groups: after one week of treatment,the FMA score of the test group was(73.59 ± 8.155)points,and the FMA score of the control group was(68.71 ± 10.799)points.There was a statistical difference between the two groups(P=0.047).After two months of treatment,the FMA score of the test group was(85.47 ± 9.449)points,and the FMA score of the control group was(76.77 ± 11.729)points.There was always a statistical difference between the two groups(P=0.002).See Table(2)and Figure 1.After one week of treatment,the ADL score of the test group was(37.65± 7.512)points in the test group and(35.65 ± 7.273)points in the control group.There was no statistically significant difference between the two groups(P=0.285).After two weeks of treatment,the ADL score of the test group was(45.16 ± 8.751)points,and the FMA score of the control group was(39.35 ± 8.635)points.There was a statistically significant difference between the two groups(P=0.010).After two months of treatment,the ADL score of the test group was(60.78 ± 10.785)points,and the ADL score of the control group was(53.06 ± 12.361)points,There was a statistical difference between the two groups(P=0.010),as shown in Table(3)and Figure 2.After 1 week of treatment,the NIHSS score of the test group was(16.63± 2.048)points in the test group and(17.55 ± 2.263)points in the control group.There was no statistically significant difference between the two groups(P=0.147).After 2 weeks of treatment,the NIHSS score of the test group was(14.63 ± 1.980)points,and the NIHSS score of the control group was(15.87 ± 2.247)points.There was a statistically significant difference between the two groups(P=0.023).After 2 months of treatment,the NIHSS score of the test group was(11.72 ± 1.971)points,and the NIHSS score of the control group was(13.35 ± 2.811)points,There was a statistical difference between the two groups(P=0.009),as shown in Table(4)and Figure 3.After 1 week of treatment,the HAMA score of the test group was(11.66 ± 2.731)points in the test group and(11.68 ± 2.600)points in the control group.The difference between the two groups was not statistically significant(P=0.975).After 2 weeks of treatment,the HAMA score of the test group was(10.00 ± 2.272)points,and the HAMA score of the control group was(10.61 ± 2.704)points.The difference between the two groups was not statistically significant(P=0.333).After 1 month of treatment,the HAMA score of the test group was(8.47 ± 1.917)points,and the HAMA score of the control group was(9.81 ± 2.535)points,There was a statistical difference between the two groups(P=0.021).After 2 months of treatment,the HAMA score of the test group was(7.69 ± 1.749)points,and the HAMA score of the control group was(9.45 ± 2.606)points.There was a statistical difference between the two groups(P=0.002).See Table(5)and Figure 4.After one week of treatment,the SDS score of the test group was(44.22± 4.956)points in the test group and(44.16 ± 6.583)points in the control group.There was no statistically significant difference between the two groups(P=0.969).After two weeks of treatment,the SDS score of the test group was(39.84 ± 5.144)points,and the SDS score of the control group was(39.74 ± 6.542)points.There was no statistically significant difference between the two groups(P=0.945).After one month of treatment,the SDS score of the test group was(35.25 ± 5.477)points,and the SDS score of the control group was(37.94 ± 6.757)points,There was no statistical difference between the two groups(P=0.088).After 2 months of treatment,the SDS score of the test group was(32.59 ± 4.872)points,and the SDS score of the control group was(36.03 ± 6.775)points.There was a statistical difference between the two groups(P=0.024).See Table(6)and Figure 5.Conclusions:1.After 8 weeks of treatment,the ADL score,FMA score,NIHSS score,HAMA score and SDS score of the test group and the control group before and after treatment were significantly different(P<0.05).2.Mindfulness therapy was positively correlated with the increase of ADL score,FMA score,NIHSS score,HAMA score and SDS scor e.3.For patients with acute cerebral infarction,mindfulness therapy is better than conventional psychological support therapy in improving limb activity,improving daily living ability,reducing anxiety and depression. |
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