The Value Of Anthropometric Screening For OSAHS

Background: Obstructive Sleep Apnea Hypopnea Syndrome(OSAHS),a common chronic disease,is closely associated with stroke,hypertension,coronary heart disease,and diabetes mellitus.OSAHS increases mortality in the adult population and imposes a serious health and economic burden on individuals and society.OSAHS diagnosis currently relies on expensive and inconvenient polysomnography monitoring,which results in many potential OSAHS patients not being diagnosed in time.Anthropometric indicators such as neck circumference,waist circumference,and Body Mass Index(BMI)have been reported to screen patients for OSAHS,but the magnitude of the screening efficacy of these anthropometric indicators and whether they are influenced by gender and age are unclear.Objective: This study intends to analyze the correlation between different anthropometric indicators and the severity of OSAHS patients,compare the screening efficacy of different anthropometric indicators for OSAHS patients,and the differences in gender and age of screening efficacy of anthropometric indicators for OSAHS patients.To explore the screening efficacy of different anthropometric indexes for OSAHS patients.Methods: The data of 836 patients with clinical symptoms of OSAHS from Xiangya Hospital of Central South University from September 2014 to August 2019 were collected in this study,excluding 2 patients younger than 18 years old,12 patients with central sleep apnea and 21 patients with mixed sleep apnea hypopnea,and finally 801 patients were included.The apnea hypopnea index(AHI)was used as the main index of severity of OSAHS,and the minimum oxygen saturation,oxygen saturation index and average oxygen saturation at night were used as secondary indexes.801 data were divided into non OSAHS and mild,moderate and severe OSAHS according to AHI.Among them,non OSAHS and mild OSAHS were classified as non-moderate-severe OSAHS group,and moderate and severe OSAHS were classified as moderate-severe OSAHS group.We analyzed the correlation between different anthropometric indicators and the severity of OSAHS,and compared the efficacy of different anthropometric indicators in screening OSAHS patients through Area Under the ROC Curve(AUC),specificity and sensitivity,as well as the impact of gender and age on screening efficacy.Results: There were significant correlations between body weight,neck circumference,waist circumference,BMI,and waist to height ratio and AHI(p < 0.001).The AUCs of weight,waist circumference,and BMI screening for OSAHS patients were all above 0.68(95% CI: 0.63-0.74),and the AUC of neck circumference and waist height ratio screening for OSAHS patients were 0.66(95%CI: 0.60-0.72).The AUC of weight,waist circumference,BMI,and neck circumference screening for patients with moderate to severe OSAHS were above 0.66(95% CI: 0.62-0.70),and the AUC of waist height ratio screening for patients with moderate to severe OSAHS was 0.64(95% CI: 0.60-0.68),and the AUC was not affected by gender or age.They have application value for screening OSAHS patients.Their screening efficacy in descending order is BMI,waist circumference,neck circumference,waist to height ratio,and weight.Conclusion:(1)BMI,waist circumference,neck circumference,waist to height ratio and weight are correlated with the severity of OSAHS,which can be used to screen OSAHS patients.There is no significant difference in the efficacy of screening OSAHS patients between different sexes and ages,so it has the application value of screening OSAHS.(2)We recommend BMI,waist circumference,neck circumference,waist to height ratio and weight as predictive indicators to build a screening model together with other predictive indicators.