Clinical Efficacy Of Yixin Dingji Decoction In The Treatment Of Ejection Fraction Preserved Heart Failure(Qi Deficiency And Blood Stasis Type) With Anxiety State

Objective: Clinical efficacy of Yixin Dingji Decoction in the treatment of ejection fraction preserved heart failure(Qi deficiency and blood stasis type)with anxiety state.Methods: Subjects with heart failure with preserved ejection fraction(Qi deficiency and blood stasis type)combined with anxiety state who met the inclusion criteria in the outpatient department of Cardiovascular Diseases of the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine from January 2021 to December 2021 were selected.A total of 60 patients who met the inclusion criteria were divided into the control group with 30 cases and the treatment group with 30 cases according to the random number table method.The control group was the conventional western medicine group.Three weeks is a course of treatment.The cardiac function(NYHA),left ventricular E/A ratio,TCM syndrome score,6-minute walk test,plasma NT-pro BNP concentration,Hamilton scale score,Minnesota Heart Failure Quality of Life Questionnaire before and after treatment were compared before and after treatment.result:1.Before treatment,there was no significant statistical difference between the two groups of patients,TCM syndrome score,6-minute walking experiment results,Minnesota quality of life score,left ventricular E/A ratio,HAMA scale score,NT-pro BNP level(P>0.05).There are no obvious statistical differences and they are comparable.2.TCM syndrome integrals: After treatment,the TCM syndrome integrals of the two groups of patients improved(P<0.05),and after the treatment of the two groups of TCM syndrome integrals,after inter-group comparison(P<0.01),the TCM syndrome integrals of the treatment group were more effective.3.Results of the 6-minute walking experiment: After treatment,the6-minute walking distance of the two groups was improved(P<0.05),and the comparison between the two groups(P<0.01)after treatment was more effective.4.Cardiac function classification: after treatment,the total effective rate of the treatment group was 93.1% higher than that of the control group of80.0%(P<0.05)and the patients in the treatment group were more effective.5.Minnesota Quality of Life Score: After treatment,both groups of patients improved their Minnesota quality of life scores(P<0.05),and after treatment in both groups,the Minnesota quality of life scores were more effective after inter-group comparison(P<0.01).6.Left ventricular E/A ratio: after treatment,the left ventricular E/A ratio was improved in both groups(P<0.05),and after treatment,the left ventricular E/A ratio of the two groups was compared with the inter-group comparison(P>0.05),and the results of the left ventricular E/A ratio in the treatment group were not shown to be more effective than those in the control group.7.HAMA scale score: after treatment,both groups of patients had an improvement in HAMA scale score(P<0.01),and after treatment,the HAMA scale score of the two groups was compared between groups(P<0.01),and the HAMA scale score of the treatment group was more effective.8.NT-pro BNP levels: after treatment,NT-pro BNP levels improved in both groups(P<0.01),and after treatment in both groups,NT-pro BNP levels were compared between groups(P<0.01),and the improvement in NT-pro BNP levels in the treatment group was more effective.Conclusion:1.The combination of Yixin Dingji Decoction with conventional western medicine was better than western medicine alone in improving 6MWT distance,enhancing cardiac function,reducing HAMA scale score,Chinese medicine evidence score,Minnesota Quality of Life Scale score,and NT-po Br NP level.2.Conventional treatment with western medicine has not shown greater efficacy compared with conventional western medicine in improving the patient’s cardiac diastolic capacity.