| Objective :To study the related risk factors and characteristics of simultaneous gastric and colonic polyps in patients with gastrointestinal co-morbidity,so as to provide evidence for clinical screening of gastrointestinal polyps and reduce the occurrence of gastrointestinal tumors.Methods : A retrospective analysis was performed on 352 patients undergoing gastroenteroscopy during their hospitalization in the Department of Gastroenterology,The First Affiliated Hospital of Jiamusi University from November 2020 to December 2021.A case-control study was adopted.Patients with gastric polyp combined with intestinal polyp were selected as the experimental group(n=102),and patients with gastric polyp alone as the control group(n=112).Patients with simple intestinal polyp were used as control group 2(n=140).Case data of all individuals were collected,including gender,age,smoking,alcohol consumption,BMI,hypertension,diabetes,HP infection,triglyceride,cholesterol,high density lipoprotein,low density lipoprotein,uric acid and other relevant factors for analysis.At the same time,the gastroenteroscopy reports of the above patients were collected,including the size,number(single,multiple)and location of polyps,as well as the pathological types of the collected pathological reports.Spss19.0 software for statistical analysis.Chi square test and binary logistic regression were used to analyze the relevant risk factors of gastrointestinal polyps,and the characteristics of polyps between groups were compared.The differences were statistically significant(P < 0.05).Results :1 General data: There were 102 cases in case group,including 42 males(41.2%)and 60 females(58.8%);there were 112 cases in control group 1,including 33males(29.5%)and 79 females(70.5%);there were 140 cases in control group 2,including 88 males(62.9%)and 52 females(37.1%);Patients were divided into five groups by age:≤40 years old,4L to 50 years old,51 to 60 years old,61 to 70 years old,and≥71 years old.In the case group,the average age was 57.30±8.66 years,and the proportion of people aged 61-70 years was the largest(39.2%),followed by people aged 51-60 years(35.3%);In control group 1,the average age was 53.88±11.07 years,and the population aged 41-50 and 51-60 years were the most,accounting for the same proportion(33.0%);In control group 2,the average age was 56.87±10.055 years old,and the proportion of people aged 51-60 years was the largest(37.1%),followed by 61-70 years old(30.0%);The proportion of people over 60 years old in the case group was 44%,The proportion of people over 60 years old in control group 1 was 27.6%,and the proportion of people over60 years old in control group 2 was 37.1%.2.Analysis results of related risk factors:Comparison between case group and control group 1: univariate analysis In the case group,the rate of patients over 60 years old,hypertension,smoking,drinking,HP infection rate,high cholesterol rate and low density lipoprotein rate were all higher than those in the control group,with statistical significance(P=0.012,0.046,0.004,0.022,0.001,0.022,0.001).Multivariate Logistic regression analysis showed that the risk factors of gastric polyp complicated with intestinal polyp were age,smoking,HP infection,and high LDL blood level(P values were 0.014,0.006,0.012,and 0.031,respectively).According to the odds ratio(OR)value,the risk factors in descending order were as follows:(OR=3.305,95%CI: 1.118--9.767),smoking(OR=3.033,95%CI :1.367--6.730),age(OR=2.281,95%CI: 1.185--4.392),HP infection(OR=2.171,95%CI: 1.1863.974).Comparison between case group and control group 2: univariate analysis: the infection rates of female and HP in case group were higher than those in control group 2,and the differences were statistically significant(P=0.001,0.001).Multivariate Logistic regression analysis showed that the risk factors of intestinal polyp complicated with gastric polyp were female and HP infection(P values were 0.001 and 0.001 respectively),and the risk factors were HP infection(OR=2.639,95%CI:1.516-4.593),female(OR=2.544,95%CI:1.463-4.424).3.Characteristics of polypsCompared with the control group 1,gastric polyps in the case group were more common with multiple gastric polyps,the size of which was usually less than 0.5cm,and the most common gastric polyps were gastric fundus glands.There were no significant differences in the number,size and pathological type of gastric polyps between the two groups(P > 0.05).Although the occurrence sites were best located in the gastric body,there were differences.The proportion of gastric polyps in the case group(39.9%)was lower than that in the control group 1(50.5%),but the proportion of gastric antral polyps(36.5%)was higher than that in the control group 1(22.9%).The difference was statistically significant(P < 0.05).Compared with the control group 2,multiple intestinal polyps were more common in both cases,the size of which was usually less than 0.5cm,mostly occurred in the left colon,and adenomatous polyps were more common.There were no significant differences in the size,location and pathological type of intestinal polyps between the two groups(P >0.05).The number of intestinal polyps was mainly multiple,but the difference was statistically significant(P < 0.05).Conclusion :1.Gastric polyps of colon polyps occurred easily merged risk factors:older than 60 years of age,smoking,HP infection,high blood LDL;Intestinal polyp patients are prone to gastric polyp risk factors: female,HP infection.2.HP infection is a risk factor for co-occurrence of gastrointestinal polyps,and HP eradication therapy is recommended.3.In simultaneous gastric and colonic polyps in the group,the gastric polyp was multiple polyps,size,often < 0.5 cm,it is better to send in gastric body,to see more fundic gland polyps;Intestinal polyps are more common in multiple polyps,with a size of less than 0.5cm,usually occurring in the left colon,and adenomatous polyps are more common. |
