Clinical Observation Of Bushen Jianpi Prescription In The Treatment Of Postmenopausal Osteoporosis With Spleen And Kidney Yang Deficiency

Objective: To evaluate the clinical efficacy of Bushen Jianpi Recipe on postmenopausal osteoporosis with spleen-kidney yang deficiency,and to provide reference for further better treatment of postmenopausal osteoporosis.Methods: 60 patients with postmenopausal osteoporosis of spleen-kidney yang deficiency type were included.They were randomly divided into two groups : 30 cases in the control group and 30 cases in the observation group.All patients were given active calcium granules.The observation group was given Bushen Jianpi prescription,and the control group was given calcitriol capsules.The course of treatment was 3 months.The basic data(age,course of disease),lumbar bone mineral density(BMD),visual analogue scale(VAS),Oswestry disability index(ODI),and clinical symptom score of TCM before and after treatment of the two groups were recorded,and the clinical efficacy was evaluated by statistical analysis.Results: 1.Comparison of lumbar BMD : After 3 months of treatment,two groups of patients with lumbar BMD levels were not significantly improved(P > 0.05).2.Analysis of curative effect of TCM symptoms : After three months of continuous treatment,the total effective rate of TCM symptom quantification score in the two groups was compared.The control group was 70 %,and the observation group was 86.67 %.The curative effect of the observation group was better than that of the control group(P <0.05).3.Comparison of TCM symptom scores : After 3 months of continuous treatment,single symptom scores were compared within the group.The main symptoms of traditional Chinese medicine : two groups of patients with eating less loose stool symptoms were significantly improved(P < 0.01);the symptoms of lumbar and knee cold pain in the observation group were significantly improved(P < 0.01),and the symptoms of lumbar and knee cold pain in the control group were significantly improved(P < 0.05).In terms of secondary symptoms of traditional Chinese medicine : two groups of patients with lumbar and knee weakness,cold and warm,abdominal distension symptoms were significantly improved(P < 0.01).4.Comparison of VAS scores : After three months of continuous treatment,the VAS scores of the two groups were significantly lower than those before treatment(P < 0.01).Compared with the control group,the observation group was more able to significantly reduce the VAS score of patients.5.Comparison of ODI indexes : After three months of continuous treatment,the ODI indexes of the two groups were significantly lower than those before treatment(P <0.01),and compared with the control group,the observation group was more able to significantly reduce the ODI indexes of patients.Conclusion: 1.Nourishing Kidney and Invigorating Spleen Prescription can significantly improve TCM syndrome scores of PMOP patients with spleen and kidney yang deficiency.2.Invigorating Kidney and Invigorating Spleen Prescription can effectively relieve the symptoms of PMOP patients with spleen and kidney yang deficiency,such as cold pain of waist and knee,loose stools,sore waist and knee,cold and warm,abdominal distension.3.Bushen Jianpi Recipe can significantly reduce the VAS score and ODI index of PMOP patients with spleen-kidney yang deficiency.